Gene: ENSG00000106211 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000106211
Transcript Identifier
ENST00000248553
Gene Type
Coding gene
Location
7 : 76302713-76304173 : positive

Family Information

Homologous gene family
HOM03P002488
(37 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P069238
(2 genes in 2 species)
specific family

Descriptions

gene_descr
heat shock 27kDa protein 1

Identifiers

Type Value
pidENSP00000248553
HGNC5246
UniprotP04792
UniprotV9HW43

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001895
IEP
Genome Projectretina homeostasis
GO:0006446
TAS
Genome Projectregulation of translational initiation
GO:0006469
ISS
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0006928
TAS
Genome Projectmovement of cell or subcellular component
GO:0006986
TAS, NAS
Genome Projectresponse to unfolded protein
GO:0009615
IEP
Genome Projectresponse to virus
GO:0010467
TAS
Genome Projectgene expression
GO:0032731
ISS
IEA
Genome Projectpositive regulation of interleukin-1 beta production
GO:0035556
IMP
Genome Projectintracellular signal transduction
GO:0035924
IMP
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0038033
IMP
Genome Projectpositive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042535
ISS
IEA
Genome Projectpositive regulation of tumor necrosis factor biosynthetic process
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0043122
ISS
IEA
Genome Projectregulation of I-kappaB kinase/NF-kappaB signaling
GO:0043536
IMP
Genome Projectpositive regulation of blood vessel endothelial cell migration
GO:0045766
IMP
Genome Projectpositive regulation of angiogenesis
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0070527
IMP
Genome Projectplatelet aggregation
GO:0071901
IEA
Genome Projectnegative regulation of protein serine/threonine kinase activity
GO:1902176
ISS
IEA
Genome Projectnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2001028
IMP
Genome Projectpositive regulation of endothelial cell chemotaxis
GO:2001234
IEA
Genome Projectnegative regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005080
ISS
IEA
Genome Projectprotein kinase C binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008426
ISS
IEA
Genome Projectprotein kinase C inhibitor activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0043130
ISS
Genome Projectubiquitin binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000502
ISS
Genome Projectproteasome complex
GO:0005615
IDA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0005819
IEA
Genome Projectspindle
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
TAS, IEA
Genome Projectcytoskeleton
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0030018
IEA
Genome ProjectZ disc
GO:0043292
IEA
Genome Projectcontractile fiber
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001436Alpha crystallin/Heat shock protein
IPR002068Alpha crystallin/Hsp20 domain
IPR008978HSP20-like chaperone
IPR031107Small heat shock protein HSP20

No MapMan annotations defined for this gene.