Gene: ENSG00000106113 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000106113
Transcript Identifier
ENST00000348438
Gene Type
Coding gene
Location
7 : 30653460-30700033 : negative

Family Information

Homologous gene family
HOM03P002772
(34 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P010002
(8 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
corticotropin releasing hormone receptor 2

Identifiers

Type Value
pidENSP00000340943
HGNC2358
UniprotQ13324

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007188
TAS
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007205
IEA
Genome Projectprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0009755
IEA
Genome Projecthormone-mediated signaling pathway
GO:0010460
IEA
Genome Projectpositive regulation of heart rate
GO:0010628
IEA
Genome Projectpositive regulation of gene expression
GO:0010629
IEA
Genome Projectnegative regulation of gene expression
GO:0010700
IEA
Genome Projectnegative regulation of norepinephrine secretion
GO:0014064
IEA
Genome Projectpositive regulation of serotonin secretion
GO:0016525
IEA
Genome Projectnegative regulation of angiogenesis
GO:0019233
IEA
Genome Projectsensory perception of pain
GO:0021549
IEA
Genome Projectcerebellum development
GO:0021854
IEA
Genome Projecthypothalamus development
GO:0030816
IEA
Genome Projectpositive regulation of cAMP metabolic process
GO:0030818
IEA
Genome Projectnegative regulation of cAMP biosynthetic process
GO:0030819
IEA
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0030855
IEA
Genome Projectepithelial cell differentiation
GO:0032755
IEA
Genome Projectpositive regulation of interleukin-6 production
GO:0032811
IEA
Genome Projectnegative regulation of epinephrine secretion
GO:0032874
IEA
Genome Projectpositive regulation of stress-activated MAPK cascade
GO:0033685
IEA
Genome Projectnegative regulation of luteinizing hormone secretion
GO:0035482
IEA
Genome Projectgastric motility
GO:0042423
IEA
Genome Projectcatecholamine biosynthetic process
GO:0043950
IEA
Genome Projectpositive regulation of cAMP-mediated signaling
GO:0043951
IEA
Genome Projectnegative regulation of cAMP-mediated signaling
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0046882
IEA
Genome Projectnegative regulation of follicle-stimulating hormone secretion
GO:0048630
IEA
Genome Projectskeletal muscle tissue growth
GO:0051092
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0060291
IEA
Genome Projectlong-term synaptic potentiation
GO:0061179
IEA
Genome Projectnegative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070372
IEA
Genome Projectregulation of ERK1 and ERK2 cascade
GO:0071376
IEA
Genome Projectcellular response to corticotropin-releasing hormone stimulus
GO:0071385
IEA
Genome Projectcellular response to glucocorticoid stimulus
GO:0090281
IEA
Genome Projectnegative regulation of calcium ion import
GO:2000252
IEA
Genome Projectnegative regulation of feeding behavior
GO:2000293
IEA
Genome Projectnegative regulation of defecation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005179
IEA
Genome Projecthormone activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0015056
TAS, IEA
Genome Projectcorticotrophin-releasing factor receptor activity
GO:0017046
IEA
Genome Projectpeptide hormone binding
GO:0043404
IEA
Genome Projectcorticotropin-releasing hormone receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005791
IEA
Genome Projectrough endoplasmic reticulum
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043196
IEA
Genome Projectvaricosity
GO:0043204
IEA
Genome Projectperikaryon
GO:0043679
IEA
Genome Projectaxon terminus
GO:0070852
IEA
Genome Projectcell body fiber

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000832GPCR, family 2, secretin-like
IPR001879GPCR, family 2, extracellular hormone receptor domain
IPR003051GPCR, family 2, corticotropin releasing factor receptor
IPR003053GPCR, family 2, corticotropin releasing factor receptor, type 2
IPR017981GPCR, family 2-like
IPR017983GPCR, family 2, secretin-like, conserved site

No MapMan annotations defined for this gene.