Gene: ENSG00000106089 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000106089
Transcript Identifier
ENST00000222812
Gene Type
Coding gene
Location
7 : 73700407-73719631 : negative

Family Information

Homologous gene family
HOM03P000568
(89 genes in 38 species)
specific family
Orthologous gene family
ORTHO03P000245
(59 genes in 37 species)
specific family

Descriptions

gene_descr
syntaxin 1A (brain)

Identifiers

Type Value
pidENSP00000222812
HGNC11433
UniprotQ16623
UniprotQ75ME0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001956
IEA
Genome Projectpositive regulation of neurotransmitter secretion
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006836
IEA
Genome Projectneurotransmitter transport
GO:0006886
IBA
IEA
Genome Projectintracellular protein transport
GO:0006887
IBA
IEA
Genome Projectexocytosis
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007269
TAS
Genome Projectneurotransmitter secretion
GO:0009629
IEA
Genome Projectresponse to gravity
GO:0010701
ISS
Genome Projectpositive regulation of norepinephrine secretion
GO:0010807
IEA
Genome Projectregulation of synaptic vesicle priming
GO:0014047
TAS
Genome Projectglutamate secretion
GO:0016081
IEA
Genome Projectsynaptic vesicle docking
GO:0016192
IEA
Genome Projectvesicle-mediated transport
GO:0017156
IEA
Genome Projectcalcium ion-dependent exocytosis
GO:0017157
IEA
Genome Projectregulation of exocytosis
GO:0031629
IBA
Genome Projectsynaptic vesicle fusion to presynaptic membrane
GO:0032940
IDA
Genome Projectsecretion by cell
GO:0033605
ISS
Genome Projectpositive regulation of catecholamine secretion
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045921
IEA
Genome Projectpositive regulation of exocytosis
GO:0045956
ISS
Genome Projectpositive regulation of calcium ion-dependent exocytosis
GO:0048278
IBA
Genome Projectvesicle docking
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:2000463
IEA
Genome Projectpositive regulation of excitatory postsynaptic potential
GO:0061025
IEA
Genome Projectmembrane fusion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000149
IBA
IEA
Genome ProjectSNARE binding
GO:0001948
IEA
Genome Projectglycoprotein binding
GO:0005484
IBA
IEA
Genome ProjectSNAP receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017022
IBA
IEA
Genome Projectmyosin binding
GO:0019855
IEA
Genome Projectcalcium channel inhibitor activity
GO:0019869
IDA
Genome Projectchloride channel inhibitor activity
GO:0019900
IPI
Genome Projectkinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0030674
IEA
Genome Projectprotein binding, bridging
GO:0032028
IEA
Genome Projectmyosin head/neck binding
GO:0043008
IEA
Genome ProjectATP-dependent protein binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0047485
IEA
Genome Projectprotein N-terminus binding
GO:0048306
IEA
Genome Projectcalcium-dependent protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0008021
IBA
IEA
Genome Projectsynaptic vesicle
GO:0012505
IBA
Genome Projectendomembrane system
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IBA
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030141
IEA
Genome Projectsecretory granule
GO:0030672
IEA
Genome Projectsynaptic vesicle membrane
GO:0031201
IDA
TAS
Genome ProjectSNARE complex
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0042641
IEA
Genome Projectactomyosin
GO:0043005
IDA
IEA
Genome Projectneuron projection
GO:0043229
IEA
Genome Projectintracellular organelle
GO:0043234
IEA
Genome Projectprotein complex
GO:0045202
IEA
Genome Projectsynapse
GO:0070032
IEA
Genome Projectsynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070033
IEA
Genome Projectsynaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
GO:0070044
IEA
Genome Projectsynaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:0008076
ISS
Genome Projectvoltage-gated potassium channel complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000727Target SNARE coiled-coil homology domain
IPR006011Syntaxin, N-terminal domain
IPR006012Syntaxin/epimorphin, conserved site
IPR010989t-SNARE
IPR028669Syntaxin 1

No MapMan annotations defined for this gene.