Gene: ENSG00000104689 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000104689
Transcript Identifier
ENST00000221132
Gene Type
Coding gene
Location
8 : 23191694-23225061 : negative

Family Information

Homologous gene family
HOM03P021291
(4 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
tumor necrosis factor receptor superfamily, member 10a

Identifiers

Type Value
pidENSP00000221132
HGNC11904
UniprotO00220

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
TAS, NAS, IEA
Genome Projectapoptotic process
GO:0006919
TAS
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165
TAS, IEA
Genome Projectsignal transduction
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007250
NAS
Genome Projectactivation of NF-kappaB-inducing kinase activity
GO:0008625
TAS, NAS
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0010939
TAS
Genome Projectregulation of necrotic cell death
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0036462
IDA
Genome ProjectTRAIL-activated apoptotic signaling pathway
GO:0043154
TAS
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266
TAS
Genome Projectnecroptotic process
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus
GO:0097191
IDA
TAS
Genome Projectextrinsic apoptotic signaling pathway
GO:0097296
TAS
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097300
TAS
Genome Projectprogrammed necrotic cell death
GO:1902041
TAS
Genome Projectregulation of extrinsic apoptotic signaling pathway via death domain receptors

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
IPI
Genome Projectprotease binding
GO:0004872
NAS
Genome Projectreceptor activity
GO:0005035
TAS
Genome Projectdeath receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0045569
NAS, IEA
Genome ProjectTRAIL binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
NAS
Genome Projectintracellular
GO:0005886
TAS
Genome Projectplasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IC, IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000488Death domain
IPR001368TNFR/NGFR cysteine-rich region
IPR011029Death-like domain
IPR020465Tumour necrosis factor receptor 10

No MapMan annotations defined for this gene.