Gene: ENSG00000104408 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000104408
Transcript Identifier
ENST00000220849
Gene Type
Coding gene
Location
8 : 108201885-108248702 : negative

Family Information

Homologous gene family
HOM03P001863
(44 genes in 37 species)
specific family

Descriptions

gene_descr
eukaryotic translation initiation factor 3, subunit E

Identifiers

Type Value
pidENSP00000220849
HGNC3277
UniprotP60228

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000184
IMP
Genome Projectnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001731
IEA
Genome Projectformation of translation preinitiation complex
GO:0006412
TAS, IEA
Genome Projecttranslation
GO:0006413
IDA
TAS, IC, IEA
Genome Projecttranslational initiation
GO:0006446
NAS, IEA
Genome Projectregulation of translational initiation
GO:0010467
TAS
Genome Projectgene expression
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0045947
NAS
Genome Projectnegative regulation of translational initiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003743
IDA
IC, IEA
Genome Projecttranslation initiation factor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0047485
IPI
Genome Projectprotein N-terminus binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
NAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005852
IDA
NAS, IEA
Genome Projecteukaryotic translation initiation factor 3 complex
GO:0016020
IDA
Genome Projectmembrane
GO:0016282
IEA
Genome Projecteukaryotic 43S preinitiation complex
GO:0016605
IDA
IEA
Genome ProjectPML body
GO:0033290
IEA
Genome Projecteukaryotic 48S preinitiation complex
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0000785
NAS
Genome Projectchromatin

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000717Proteasome component (PCI) domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR016650Eukaryotic translation initiation factor 3 subunit E
IPR019010Eukaryotic translation initiation factor 3 subunit E, N-terminal

No MapMan annotations defined for this gene.