Gene: ENSG00000102879 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000102879
Transcript Identifier
ENST00000570045
Gene Type
Coding gene
Location
16 : 30185210-30188964 : positive

Family Information

Homologous gene family
HOM03P003191
(30 genes in 14 species)
specific family
Orthologous gene family
ORTHO03P003945
(21 genes in 14 species)
specific family

Descriptions

gene_descr
coronin, actin binding protein, 1A

Identifiers

Type Value
pidENSP00000455552
HGNC2252
UniprotP31146
UniprotA0A024R611

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001845
IMP
IEA
Genome Projectphagolysosome assembly
GO:0006816
IEA
Genome Projectcalcium ion transport
GO:0007015
IEA
Genome Projectactin filament organization
GO:0008064
IEA
Genome Projectregulation of actin polymerization or depolymerization
GO:0008360
IEA
Genome Projectregulation of cell shape
GO:0016477
IEA
Genome Projectcell migration
GO:0030335
IEA
Genome Projectpositive regulation of cell migration
GO:0030595
IEA
Genome Projectleukocyte chemotaxis
GO:0030833
IEA
Genome Projectregulation of actin filament polymerization
GO:0031339
IEA
Genome Projectnegative regulation of vesicle fusion
GO:0032796
IEA
Genome Projecturopod organization
GO:0034097
IEA
Genome Projectresponse to cytokine
GO:0038180
IEA
Genome Projectnerve growth factor signaling pathway
GO:0042102
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0043029
IEA
Genome ProjectT cell homeostasis
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0048873
IEA
Genome Projecthomeostasis of number of cells within a tissue
GO:0050870
IEA
Genome Projectpositive regulation of T cell activation
GO:0051279
IEA
Genome Projectregulation of release of sequestered calcium ion into cytosol
GO:0061502
IEA
Genome Projectearly endosome to recycling endosome transport
GO:0071353
IEA
Genome Projectcellular response to interleukin-4
GO:0006909
IMP
Genome Projectphagocytosis
GO:0006928
NAS
Genome Projectmovement of cell or subcellular component
GO:0030036
IMP
Genome Projectactin cytoskeleton organization
GO:0031589
IMP
Genome Projectcell-substrate adhesion
GO:0032956
IMP
Genome Projectregulation of actin cytoskeleton organization
GO:0043320
IMP
Genome Projectnatural killer cell degranulation
GO:0045087
NAS
Genome Projectinnate immune response
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0051126
IDA
Genome Projectnegative regulation of actin nucleation
GO:0001771
IMP
Genome Projectimmunological synapse formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008092
ISS
IEA
Genome Projectcytoskeletal protein binding
GO:0042802
IEA
Genome Projectidentical protein binding
GO:0051015
IDA, IMP
IEA
Genome Projectactin filament binding
GO:0003779
IPI
IEA
Genome Projectactin binding
GO:0003785
IMP
Genome Projectactin monomer binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0032036
IPI
Genome Projectmyosin heavy chain binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0043548
IDA
Genome Projectphosphatidylinositol 3-kinase binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
IEA
Genome Projectimmunological synapse
GO:0005769
IEA
Genome Projectearly endosome
GO:0005911
IEA
Genome Projectcell-cell junction
GO:0015629
IBA
IEA
Genome Projectactin cytoskeleton
GO:0030424
IEA
Genome Projectaxon
GO:0031252
IEA
Genome Projectcell leading edge
GO:0001891
IDA
Genome Projectphagocytic cup
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005884
IDA
Genome Projectactin filament
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005938
IEA
Genome Projectcell cortex
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0030027
IDA
Genome Projectlamellipodium
GO:0030670
IEA
Genome Projectphagocytic vesicle membrane
GO:0030864
IDA
Genome Projectcortical actin cytoskeleton
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043234
IDA
Genome Projectprotein complex
GO:0045335
IDA
Genome Projectphagocytic vesicle
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0005634
IDA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001680WD40 repeat
IPR015048Domain of unknown function DUF1899
IPR015049Trimerisation motif
IPR015505Coronin
IPR015943WD40/YVTN repeat-like-containing domain
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site
IPR029508Coronin 1A

No MapMan annotations defined for this gene.