Gene: ENSG00000102145 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000102145
Transcript Identifier
ENST00000376670
Gene Type
Coding gene
Location
X : 48791110-48794164 : positive

Family Information

Homologous gene family
HOM03P002506
(37 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P075106
(2 genes in 2 species)
specific family

Descriptions

gene_descr
GATA binding protein 1 (globin transcription factor 1)

Identifiers

Type Value
pidENSP00000365858
HGNC4170
UniprotP15976

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007267
IEA
Genome Projectcell-cell signaling
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008584
IMP
Genome Projectmale gonad development
GO:0010559
IMP
Genome Projectregulation of glycoprotein biosynthetic process
GO:0010724
IDA
Genome Projectregulation of definitive erythrocyte differentiation
GO:0030099
IEA
Genome Projectmyeloid cell differentiation
GO:0030218
IEP
IEA
Genome Projecterythrocyte differentiation
GO:0030219
IMP
IEA
Genome Projectmegakaryocyte differentiation
GO:0030220
IMP
Genome Projectplatelet formation
GO:0030221
IEP
IEA
Genome Projectbasophil differentiation
GO:0030222
IEP
IEA
Genome Projecteosinophil differentiation
GO:0030502
IEA
Genome Projectnegative regulation of bone mineralization
GO:0033690
IEA
Genome Projectpositive regulation of osteoblast proliferation
GO:0035162
IEA
Genome Projectembryonic hemopoiesis
GO:0035854
IDA
Genome Projecteosinophil fate commitment
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0045648
IMP
Genome Projectpositive regulation of erythrocyte differentiation
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048468
IEA
Genome Projectcell development
GO:0048821
IMP
IEA
Genome Projecterythrocyte development
GO:0050731
IMP
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0070527
IMP
Genome Projectplatelet aggregation
GO:0071733
ISS
IEA
Genome Projecttranscriptional activation by promoter-enhancer looping
GO:0097028
IEA
Genome Projectdendritic cell differentiation
GO:0097067
IDA
Genome Projectcellular response to thyroid hormone stimulus
GO:2000678
IDA
Genome Projectnegative regulation of transcription regulatory region DNA binding
GO:2001240
IMP
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000976
IMP
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979
IMP
Genome ProjectRNA polymerase II core promoter sequence-specific DNA binding
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001047
IDA
Genome Projectcore promoter binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001078
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085
IPI
Genome ProjectRNA polymerase II transcription factor binding
GO:0001158
IEA
Genome Projectenhancer sequence-specific DNA binding
GO:0002039
IEA
Genome Projectp53 binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008301
IEA
Genome ProjectDNA binding, bending
GO:0031490
IDA
Genome Projectchromatin DNA binding
GO:0043565
IMP
IEA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070742
IPI
Genome ProjectC2H2 zinc finger domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0017053
IDA
Genome Projecttranscriptional repressor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000679Zinc finger, GATA-type
IPR013088Zinc finger, NHR/GATA-type
IPR029524Transcription factor GATA-1

No MapMan annotations defined for this gene.