Gene: ENSG00000101204 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000101204
Transcript Identifier
ENST00000370263
Gene Type
Coding gene
Location
20 : 63346738-63361165 : negative

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P006938
(12 genes in 5 species)
specific family

Descriptions

gene_descr
cholinergic receptor, nicotinic, alpha 4 (neuronal)

Identifiers

Type Value
pidENSP00000359285
HGNC1958
UniprotP43681

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001508
ISS
IEA
Genome Projectaction potential
GO:0001666
IDA
Genome Projectresponse to hypoxia
GO:0006281
IMP
Genome ProjectDNA repair
GO:0006810
IEA
Genome Projecttransport
GO:0006811
NAS, IEA
Genome Projection transport
GO:0006816
ISS
IEA
Genome Projectcalcium ion transport
GO:0006979
IMP
Genome Projectresponse to oxidative stress
GO:0007165
IDA
Genome Projectsignal transduction
GO:0007268
TAS, NAS
Genome Projectsynaptic transmission
GO:0007271
ISS, IBA
IEA
Genome Projectsynaptic transmission, cholinergic
GO:0007274
IBA
Genome Projectneuromuscular synaptic transmission
GO:0007585
IEA
Genome Projectrespiratory gaseous exchange
GO:0007626
IEA
Genome Projectlocomotory behavior
GO:0014059
ISS
IEA
Genome Projectregulation of dopamine secretion
GO:0019233
ISS
IEA
Genome Projectsensory perception of pain
GO:0034220
TAS, IEA
Genome Projection transmembrane transport
GO:0035094
IDA
Genome Projectresponse to nicotine
GO:0035095
IMP
Genome Projectbehavioral response to nicotine
GO:0035640
IEA
Genome Projectexploration behavior
GO:0042113
ISS
IEA
Genome ProjectB cell activation
GO:0042391
ISS, IBA
IEA
Genome Projectregulation of membrane potential
GO:0050877
IMP
Genome Projectneurological system process
GO:0050890
IMP
Genome Projectcognition
GO:0051899
ISS
IEA
Genome Projectmembrane depolarization
GO:0060080
ISS
IEA
Genome Projectinhibitory postsynaptic potential
GO:0098655
IDA
TAS, IEA
Genome Projectcation transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004889
IDA
TAS, IEA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0015276
TAS
Genome Projectligand-gated ion channel activity
GO:0015464
IDA
Genome Projectacetylcholine receptor activity
GO:0042166
IBA
IC
Genome Projectacetylcholine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
ISS
TAS, IEA
Genome Projectplasma membrane
GO:0005892
IDA
Genome Projectacetylcholine-gated channel complex
GO:0009897
ISS
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
ISS
IEA
Genome Projectmembrane
GO:0016021
NAS, IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
ISS
Genome Projectdendrite
GO:0043005
IBA
Genome Projectneuron projection
GO:0043025
ISS
Genome Projectneuronal cell body
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002394Nicotinic acetylcholine receptor
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.