Gene: ENSG00000101180 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000101180
Transcript Identifier
ENST00000340177
Gene Type
Coding gene
Location
20 : 62216006-62219970 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P069409
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
histamine receptor H3

Identifiers

Type Value
pidENSP00000342560
HGNC5184
UniprotQ9Y5N1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001505
IEA
Genome Projectregulation of neurotransmitter levels
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007194
IBA
Genome Projectnegative regulation of adenylate cyclase activity
GO:0007269
TAS
Genome Projectneurotransmitter secretion
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0014050
IBA
Genome Projectnegative regulation of glutamate secretion
GO:0014061
IBA
Genome Projectregulation of norepinephrine secretion
GO:0014063
IBA
Genome Projectnegative regulation of serotonin secretion
GO:0050890
IBA
Genome Projectcognition
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004969
TAS, IEA
Genome Projecthistamine receptor activity
GO:0051381
IBA
Genome Projecthistamine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR003980Histamine H3 receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.