Gene: ENSG00000101144 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000101144
Transcript Identifier
ENST00000395863
Gene Type
Coding gene
Location
20 : 57170959-57266122 : negative

Family Information

Homologous gene family
HOM03P001000
(62 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P010583
(8 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
bone morphogenetic protein 7

Identifiers

Type Value
pidENSP00000379204
HGNC1074
UniprotP18075
UniprotA8K571

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001654
IEA
Genome Projecteye development
GO:0001657
ISS
IEA
Genome Projectureteric bud development
GO:0001707
IEA
Genome Projectmesoderm formation
GO:0001822
IEA
Genome Projectkidney development
GO:0007389
IEA
Genome Projectpattern specification process
GO:0007411
IEA
Genome Projectaxon guidance
GO:0007435
IEA
Genome Projectsalivary gland morphogenesis
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009880
IEA
Genome Projectembryonic pattern specification
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0030326
IEA
Genome Projectembryonic limb morphogenesis
GO:0030855
IEA
Genome Projectepithelial cell differentiation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033280
IEA
Genome Projectresponse to vitamin D
GO:0035239
IEA
Genome Projecttube morphogenesis
GO:0040007
IEA
Genome Projectgrowth
GO:0042325
IEA
Genome Projectregulation of phosphorylation
GO:0042475
IEA
Genome Projectodontogenesis of dentin-containing tooth
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0045597
IEA
Genome Projectpositive regulation of cell differentiation
GO:0045665
IDA
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045746
IEA
Genome Projectnegative regulation of Notch signaling pathway
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048468
IBA
IEA
Genome Projectcell development
GO:0048593
IEA
Genome Projectcamera-type eye morphogenesis
GO:0048596
IEA
Genome Projectembryonic camera-type eye morphogenesis
GO:0048646
IEA
Genome Projectanatomical structure formation involved in morphogenesis
GO:0048754
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048812
IDA
IEA
Genome Projectneuron projection morphogenesis
GO:0050768
IEA
Genome Projectnegative regulation of neurogenesis
GO:0060272
IEA
Genome Projectembryonic skeletal joint morphogenesis
GO:0060445
IEA
Genome Projectbranching involved in salivary gland morphogenesis
GO:0060485
ISS
IEA
Genome Projectmesenchyme development
GO:0060686
IEA
Genome Projectnegative regulation of prostatic bud formation
GO:0060687
IEA
Genome Projectregulation of branching involved in prostate gland morphogenesis
GO:0072040
IEA
Genome Projectnegative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072133
IEA
Genome Projectmetanephric mesenchyme morphogenesis
GO:0072134
IEA
Genome Projectnephrogenic mesenchyme morphogenesis
GO:0072136
IEA
Genome Projectmetanephric mesenchymal cell proliferation involved in metanephros development
GO:0001501
TAS
Genome Projectskeletal system development
GO:0001503
IEA
Genome Projectossification
GO:0001656
IEP
Genome Projectmetanephros development
GO:0001823
IEP
Genome Projectmesonephros development
GO:0001837
TAS
Genome Projectepithelial to mesenchymal transition
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0010664
ISS
Genome Projectnegative regulation of striated muscle cell apoptotic process
GO:0010800
IDA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010862
IDA
TAS
Genome Projectpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016358
TAS
Genome Projectdendrite development
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0030501
IDA
Genome Projectpositive regulation of bone mineralization
GO:0030509
IDA, IMP
Genome ProjectBMP signaling pathway
GO:0032088
ISS
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0034116
IDA
Genome Projectpositive regulation of heterotypic cell-cell adhesion
GO:0034504
IDA
Genome Projectprotein localization to nucleus
GO:0042326
IDA
Genome Projectnegative regulation of phosphorylation
GO:0042347
ISS
Genome Projectnegative regulation of NF-kappaB import into nucleus
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0043401
IMP
Genome Projectsteroid hormone mediated signaling pathway
GO:0043407
IDA
Genome Projectnegative regulation of MAP kinase activity
GO:0045669
IDA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045786
IDA
Genome Projectnegative regulation of cell cycle
GO:0045839
IDA
Genome Projectnegative regulation of mitotic nuclear division
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048762
IDA
Genome Projectmesenchymal cell differentiation
GO:0051216
IEA
Genome Projectcartilage development
GO:0060393
IDA
Genome Projectregulation of pathway-restricted SMAD protein phosphorylation
GO:0060395
IDA
Genome ProjectSMAD protein signal transduction
GO:0060548
IDA
Genome Projectnegative regulation of cell death
GO:0070487
IDA
Genome Projectmonocyte aggregation
GO:0071456
ISS
Genome Projectcellular response to hypoxia
GO:0071773
IMP
Genome Projectcellular response to BMP stimulus
GO:0072125
IDA
Genome Projectnegative regulation of glomerular mesangial cell proliferation
GO:1900006
IDA
Genome Projectpositive regulation of dendrite development
GO:1900106
IDA
Genome Projectpositive regulation of hyaluranon cable assembly
GO:2000121
ISS
Genome Projectregulation of removal of superoxide radicals

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0008201
IEA
Genome Projectheparin binding
GO:0005125
IBA
IEA
Genome Projectcytokine activity
GO:0005160
IBA
Genome Projecttransforming growth factor beta receptor binding
GO:0070700
IBA
Genome ProjectBMP receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0031012
IEA
Genome Projectextracellular matrix
GO:0031988
IEA
Genome Projectmembrane-bounded vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001111Transforming growth factor-beta, N-terminal
IPR001839Transforming growth factor-beta, C-terminal
IPR015615Transforming growth factor-beta-related
IPR017948Transforming growth factor beta, conserved site
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.