Gene: ENSG00000100448 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000100448
Transcript Identifier
ENST00000216336
Gene Type
Coding gene
Location
14 : 24573637-24576223 : negative

Family Information

Homologous gene family
HOM03P000033
(649 genes in 22 species)
specific family
Orthologous gene family
ORTHO03P063350
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
cathepsin G

Identifiers

Type Value
pidENSP00000216336
HGNC2532
UniprotP08311

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002003
TAS
Genome Projectangiotensin maturation
GO:0006468
IDA
Genome Projectprotein phosphorylation
GO:0006508
IDA
IEA
Genome Projectproteolysis
GO:0006955
TAS
Genome Projectimmune response
GO:0016485
IBA
Genome Projectprotein processing
GO:0022617
TAS
Genome Projectextracellular matrix disassembly
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0042742
IEA
Genome Projectdefense response to bacterium
GO:0044130
IEA
Genome Projectnegative regulation of growth of symbiont in host
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0050778
IEA
Genome Projectpositive regulation of immune response
GO:0050830
IEA
Genome Projectdefense response to Gram-positive bacterium
GO:0050832
IEA
Genome Projectdefense response to fungus
GO:0070946
IEA
Genome Projectneutrophil mediated killing of gram-positive bacterium

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004252
IDA
IEA
Genome Projectserine-type endopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008201
IDA
Genome Projectheparin binding
GO:0008233
IDA
IEA
Genome Projectpeptidase activity
GO:0008236
IEA
Genome Projectserine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IBA
Genome Projectcytoplasm
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0030141
IDA
Genome Projectsecretory granule
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0031012
IDA
Genome Projectextracellular matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001254Serine proteases, trypsin domain
IPR001314Peptidase S1A, chymotrypsin-type
IPR009003Peptidase S1, PA clan
IPR018114Peptidase S1, trypsin family, active site

No MapMan annotations defined for this gene.