Gene: ENSG00000100219 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000100219
Transcript Identifier
ENST00000344347
Gene Type
Coding gene
Location
22 : 28795175-28800524 : negative

Family Information

Homologous gene family
HOM03P020555
(4 genes in 4 species)
specific family

Descriptions

gene_descr
X-box binding protein 1

Identifiers

Type Value
pidENSP00000343155
HGNC12801
UniprotP17861

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001525
ISS
IEA
Genome Projectangiogenesis
GO:0001889
ISS
IEA
Genome Projectliver development
GO:0001934
IDA
Genome Projectpositive regulation of protein phosphorylation
GO:0001935
IDA
Genome Projectendothelial cell proliferation
GO:0002070
IEA
Genome Projectepithelial cell maturation
GO:0002639
IDA
Genome Projectpositive regulation of immunoglobulin production
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
ISS
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006511
ISS
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006633
TAS
Genome Projectfatty acid biosynthetic process
GO:0006810
IEA
Genome Projecttransport
GO:0006914
IEA
Genome Projectautophagy
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006955
TAS
Genome Projectimmune response
GO:0006986
IEA
Genome Projectresponse to unfolded protein
GO:0006990
IDA
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007517
IEA
Genome Projectmuscle organ development
GO:0010506
IEA
Genome Projectregulation of autophagy
GO:0010508
IDA
Genome Projectpositive regulation of autophagy
GO:0010832
ISS
IEA
Genome Projectnegative regulation of myotube differentiation
GO:0014065
IDA
Genome Projectphosphatidylinositol 3-kinase signaling
GO:0015031
IEA
Genome Projectprotein transport
GO:0016049
IDA
Genome Projectcell growth
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030968
ISS
TAS, IEA
Genome Projectendoplasmic reticulum unfolded protein response
GO:0031017
IEA
Genome Projectexocrine pancreas development
GO:0031062
IDA
Genome Projectpositive regulation of histone methylation
GO:0031647
IDA
Genome Projectregulation of protein stability
GO:0031648
IDA, IMP
Genome Projectprotein destabilization
GO:0031670
ISS
IEA
Genome Projectcellular response to nutrient
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032869
ISS
IEA
Genome Projectcellular response to insulin stimulus
GO:0034599
IDA
Genome Projectcellular response to oxidative stress
GO:0034976
IDA
Genome Projectresponse to endoplasmic reticulum stress
GO:0035356
ISS
IEA
Genome Projectcellular triglyceride homeostasis
GO:0035924
IDA
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0036498
TAS
Genome ProjectIRE1-mediated unfolded protein response
GO:0036500
TAS
Genome ProjectATF6-mediated unfolded protein response
GO:0042149
ISS
IEA
Genome Projectcellular response to glucose starvation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042593
IEA
Genome Projectglucose homeostasis
GO:0042632
ISS
IEA
Genome Projectcholesterol homeostasis
GO:0042993
IDA
Genome Projectpositive regulation of transcription factor import into nucleus
GO:0043066
ISS
IEA
Genome Projectnegative regulation of apoptotic process
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0045348
IMP
Genome Projectpositive regulation of MHC class II biosynthetic process
GO:0045579
IDA
Genome Projectpositive regulation of B cell differentiation
GO:0045582
IDA
Genome Projectpositive regulation of T cell differentiation
GO:0045600
ISS
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045944
IDA, IMP
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048010
IDA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048666
ISS
IEA
Genome Projectneuron development
GO:0051024
ISS
IEA
Genome Projectpositive regulation of immunoglobulin secretion
GO:0051602
IEA
Genome Projectresponse to electrical stimulus
GO:0055089
ISS
IEA
Genome Projectfatty acid homeostasis
GO:0055092
ISS
IEA
Genome Projectsterol homeostasis
GO:0060096
IEA
Genome Projectserotonin secretion, neurotransmission
GO:0060612
ISS
IEA
Genome Projectadipose tissue development
GO:0060691
IEA
Genome Projectepithelial cell maturation involved in salivary gland development
GO:0070059
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071222
IDA
Genome Projectcellular response to lipopolysaccharide
GO:0071230
ISS
IEA
Genome Projectcellular response to amino acid stimulus
GO:0071236
IEA
Genome Projectcellular response to antibiotic
GO:0071332
ISS
IEA
Genome Projectcellular response to fructose stimulus
GO:0071333
ISS
IEA
Genome Projectcellular response to glucose stimulus
GO:0071353
ISS
IEA
Genome Projectcellular response to interleukin-4
GO:0071375
ISS
IEA
Genome Projectcellular response to peptide hormone stimulus
GO:0071498
IDA
Genome Projectcellular response to fluid shear stress
GO:0071499
IDA
Genome Projectcellular response to laminar fluid shear stress
GO:1900100
IDA
Genome Projectpositive regulation of plasma cell differentiation
GO:1900102
IDA
Genome Projectnegative regulation of endoplasmic reticulum unfolded protein response
GO:1900103
IMP
Genome Projectpositive regulation of endoplasmic reticulum unfolded protein response
GO:1900413
TAS
Genome Projectpositive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
GO:1901800
IEA
Genome Projectpositive regulation of proteasomal protein catabolic process
GO:1901985
IDA
Genome Projectpositive regulation of protein acetylation
GO:1902236
IDA
IEA
Genome Projectnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903071
TAS
Genome Projectpositive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1903489
ISS
IEA
Genome Projectpositive regulation of lactation
GO:1990418
ISS
IEA
Genome Projectresponse to insulin-like growth factor stimulus
GO:1990440
TAS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:2000347
ISS
IEA
Genome Projectpositive regulation of hepatocyte proliferation
GO:2000353
IDA
Genome Projectpositive regulation of endothelial cell apoptotic process
GO:2000778
ISS
IEA
Genome Projectpositive regulation of interleukin-6 secretion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001047
ISS
IEA
Genome Projectcore promoter binding
GO:0001085
IEA
Genome ProjectRNA polymerase II transcription factor binding
GO:0001158
IDA
Genome Projectenhancer sequence-specific DNA binding
GO:0002020
IPI
Genome Projectprotease binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003700
IDA
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0030331
TAS
Genome Projectestrogen receptor binding
GO:0031490
IDA
Genome Projectchromatin DNA binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0036312
IEA
Genome Projectphosphatidylinositol 3-kinase regulatory subunit binding
GO:0042803
TAS
Genome Projectprotein homodimerization activity
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
IDA
TAS
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
ISS
IEA
Genome Projectcytoplasm
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
IDA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030176
IDA
Genome Projectintegral component of endoplasmic reticulum membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004827Basic-leucine zipper domain

No MapMan annotations defined for this gene.