Gene: ENSG00000100146 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000100146
Transcript Identifier
ENST00000360880
Gene Type
Coding gene
Location
22 : 37973495-37983784 : negative

Family Information

Homologous gene family
HOM03P001338
(53 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P066212
(2 genes in 2 species)
specific family

Descriptions

gene_descr
SRY (sex determining region Y)-box 10

Identifiers

Type Value
pidENSP00000354130
HGNC11190
UniprotP56693
UniprotA0A024R1N6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001755
IEA
Genome Projectneural crest cell migration
GO:0002052
IEA
Genome Projectpositive regulation of neuroblast proliferation
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007422
IEA
Genome Projectperipheral nervous system development
GO:0014015
IEA
Genome Projectpositive regulation of gliogenesis
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030318
IEA
Genome Projectmelanocyte differentiation
GO:0032808
IEA
Genome Projectlacrimal gland development
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048469
IEA
Genome Projectcell maturation
GO:0048484
IEA
Genome Projectenteric nervous system development
GO:0048546
IEA
Genome Projectdigestive tract morphogenesis
GO:0048589
IEA
Genome Projectdevelopmental growth
GO:0048709
IEA
Genome Projectoligodendrocyte differentiation
GO:0048863
IEA
Genome Projectstem cell differentiation
GO:0061138
IEA
Genome Projectmorphogenesis of a branching epithelium
GO:0090090
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006357
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980
IEA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001190
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0044212
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0003713
TAS
Genome Projecttranscription coactivator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0042802
IPI
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0031315
IEA
Genome Projectextrinsic component of mitochondrial outer membrane
GO:0005634
IDA
ISS
IEA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009071High mobility group box domain
IPR022151Sox developmental protein N-terminal

No MapMan annotations defined for this gene.