Gene: ENSG00000099985 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000099985
Transcript Identifier
ENST00000215781
Gene Type
Coding gene
Location
22 : 30263883-30266799 : negative

Family Information

Homologous gene family
HOM03P114013
(orphan gene)
specific family

Descriptions

gene_descr
oncostatin M

Identifiers

Type Value
pidENSP00000215781
HGNC8506
UniprotP13725

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002675
IC
Genome Projectpositive regulation of acute inflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0007275
TAS
Genome Projectmulticellular organismal development
GO:0007422
IEA
Genome Projectperipheral nervous system development
GO:0008283
TAS
Genome Projectcell proliferation
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008285
TAS
Genome Projectnegative regulation of cell proliferation
GO:0009408
IEA
Genome Projectresponse to heat
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0038165
IDA
Genome Projectoncostatin-M-mediated signaling pathway
GO:0040008
IEA
Genome Projectregulation of growth
GO:0042503
IEA
Genome Projecttyrosine phosphorylation of Stat3 protein
GO:0042506
IEA
Genome Projecttyrosine phosphorylation of Stat5 protein
GO:0042508
IEA
Genome Projecttyrosine phosphorylation of Stat1 protein
GO:0042517
IDA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043410
IDA
Genome Projectpositive regulation of MAPK cascade
GO:0045835
IEA
Genome Projectnegative regulation of meiotic nuclear division
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046888
IDA
Genome Projectnegative regulation of hormone secretion
GO:0048266
IEA
Genome Projectbehavioral response to pain
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0051781
IEA
Genome Projectpositive regulation of cell division
GO:2001235
IEA
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IDA
TAS, IEA
Genome Projectcytokine activity
GO:0005147
IPI
TAS
Genome Projectoncostatin-M receptor binding
GO:0008083
IDA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001581Leukemia inhibitory factor /oncostatin
IPR009079Four-helical cytokine-like, core
IPR012351Four-helical cytokine, core
IPR019827Leukemia inhibitory factor /oncostatin, conserved site

No MapMan annotations defined for this gene.