Gene: ENSG00000096433 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000096433
Transcript Identifier
ENST00000605930
Gene Type
Coding gene
Location
6 : 33621603-33695780 : positive

Family Information

Homologous gene family
HOM03P001263
(54 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P008296
(10 genes in 6 species)
specific family

Descriptions

gene_descr
inositol 1,4,5-trisphosphate receptor, type 3

Identifiers

Type Value
pidENSP00000475177
HGNC6182
UniprotQ14573

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006816
IEA
Genome Projectcalcium ion transport
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007186
ISS
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007202
TAS
Genome Projectactivation of phospholipase C activity
GO:0007204
ISS
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007596
TAS
Genome Projectblood coagulation
GO:0007613
IEA
Genome Projectmemory
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0030168
TAS
Genome Projectplatelet activation
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038096
TAS
Genome ProjectFc-gamma receptor signaling pathway involved in phagocytosis
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048010
TAS
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048016
IDA
ISS
IEA
Genome Projectinositol phosphate-mediated signaling
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:0050913
IEA
Genome Projectsensory perception of bitter taste
GO:0050916
IEA
Genome Projectsensory perception of sweet taste
GO:0050917
IEA
Genome Projectsensory perception of umami taste
GO:0051260
ISS
Genome Projectprotein homooligomerization
GO:0051291
ISS
Genome Projectprotein heterooligomerization
GO:0051592
IDA
Genome Projectresponse to calcium ion
GO:0055085
IEA
Genome Projecttransmembrane transport
GO:0060291
IEA
Genome Projectlong-term synaptic potentiation
GO:0060402
ISS
IEA
Genome Projectcalcium ion transport into cytosol
GO:0070588
IEA
Genome Projectcalcium ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000822
ISS
Genome Projectinositol hexakisphosphate binding
GO:0005216
IEA
Genome Projection channel activity
GO:0005218
ISS
IEA
Genome Projectintracellular ligand-gated calcium channel activity
GO:0005220
IDA
ISS
IEA
Genome Projectinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262
IEA
Genome Projectcalcium channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0035091
IEA
Genome Projectphosphatidylinositol binding
GO:0043533
ISS
Genome Projectinositol 1,3,4,5 tetrakisphosphate binding
GO:0070679
IDA
Genome Projectinositol 1,4,5 trisphosphate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005640
ISS
Genome Projectnuclear outer membrane
GO:0005654
IEA
Genome Projectnucleoplasm
GO:0005730
IEA
Genome Projectnucleolus
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005783
ISS
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IDA
ISS
TAS, IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
ISS
Genome Projectcytosol
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005887
IDA
Genome Projectintegral component of plasma membrane
GO:0005903
ISS
Genome Projectbrush border
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031095
TAS
Genome Projectplatelet dense tubular network membrane
GO:0043025
ISS
Genome Projectneuronal cell body
GO:0043209
ISS
Genome Projectmyelin sheath
GO:0043235
IDA
Genome Projectreceptor complex
GO:0045177
ISS
Genome Projectapical part of cell

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000493Inositol 1,4,5-trisphosphate-binding protein receptor
IPR000699RIH (RyR and IP3R Homology) domain
IPR005821Ion transport domain
IPR013662RyR/IP3R Homology associated domain
IPR014821Inositol 1,4,5-trisphosphate/ryanodine receptor
IPR015925Ryanodine receptor-related
IPR016093MIR motif

No MapMan annotations defined for this gene.