Gene: ENSG00000096384 (Homo sapiens)

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Gene Identifier
ENSG00000096384
Transcript Identifier
ENST00000371554
Gene Type
Coding gene
Location
6 : 44248630-44253598 : positive

Family Information

Homologous gene family
HOM03P000172
(184 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000033
(141 genes in 39 species)
specific family

Descriptions

gene_descr
heat shock protein 90kDa alpha (cytosolic), class B member 1

Identifiers

Type Value
pidENSP00000360609
HGNC5258
UniprotP08238
UniprotA0A024RD80

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001890
IEA
Genome Projectplacenta development
GO:0006457
IEA
Genome Projectprotein folding
GO:0006950
IEA
Genome Projectresponse to stress
GO:0009651
IEA
Genome Projectresponse to salt stress
GO:0032092
IEA
Genome Projectpositive regulation of protein binding
GO:0033160
IEA
Genome Projectpositive regulation of protein import into nucleus, translocation
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045793
IEA
Genome Projectpositive regulation of cell size
GO:0071353
IEA
Genome Projectcellular response to interleukin-4
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0071902
IEA
Genome Projectpositive regulation of protein serine/threonine kinase activity
GO:0006986
NAS
Genome Projectresponse to unfolded protein
GO:0007411
TAS
Genome Projectaxon guidance
GO:0019062
IMP
Genome Projectvirion attachment to host cell
GO:0032435
IMP
Genome Projectnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034605
TAS
Genome Projectcellular response to heat
GO:0035872
TAS
Genome Projectnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038096
TAS
Genome ProjectFc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045429
ISS
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0060334
IMP
Genome Projectregulation of interferon-gamma-mediated signaling pathway
GO:0060338
IMP
Genome Projectregulation of type I interferon-mediated signaling pathway
GO:0097435
IMP
Genome Projectfibril organization
GO:1900034
TAS
Genome Projectregulation of cellular response to heat

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002134
IEA
Genome ProjectUTP binding
GO:0002135
IEA
Genome ProjectCTP binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0017098
IEA
Genome Projectsulfonylurea receptor binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0032564
IEA
Genome ProjectdATP binding
GO:0044325
IEA
Genome Projection channel binding
GO:0051082
IEA
Genome Projectunfolded protein binding
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003725
IDA
Genome Projectdouble-stranded RNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0023026
IDA
Genome ProjectMHC class II protein complex binding
GO:0030235
ISS
Genome Projectnitric-oxide synthase regulator activity
GO:0030911
ISS
Genome ProjectTPR domain binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0009986
IEA
Genome Projectcell surface
GO:0016234
IEA
Genome Projectinclusion body
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0016324
IEA
Genome Projectapical plasma membrane
GO:0031526
IEA
Genome Projectbrush border membrane
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0016020
IDA
Genome Projectmembrane
GO:0042470
IEA
Genome Projectmelanosome
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0008180
IDA
Genome ProjectCOP9 signalosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001404Heat shock protein Hsp90 family
IPR003594Histidine kinase-like ATPase, C-terminal domain
IPR019805Heat shock protein Hsp90, conserved site
IPR020568Ribosomal protein S5 domain 2-type fold
IPR020575Heat shock protein Hsp90, N-terminal

No MapMan annotations defined for this gene.