Gene: ENSG00000091513 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000091513
Transcript Identifier
ENST00000402696
Gene Type
Coding gene
Location
3 : 133746441-133778620 : positive

Family Information

Homologous gene family
HOM03P006668
(13 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P024866
(4 genes in 3 species)
specific family

Descriptions

gene_descr
transferrin

Identifiers

Type Value
pidENSP00000385834
HGNC11740
UniprotP02787

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001895
IEP
Genome Projectretina homeostasis
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006826
IEA
Genome Projectiron ion transport
GO:0006879
TAS, IEA
Genome Projectcellular iron ion homeostasis
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007257
IEA
Genome Projectactivation of JUN kinase activity
GO:0007596
TAS
Genome Projectblood coagulation
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030316
IEA
Genome Projectosteoclast differentiation
GO:0031647
TAS
Genome Projectregulation of protein stability
GO:0033572
TAS
Genome Projecttransferrin transport
GO:0042327
IEA
Genome Projectpositive regulation of phosphorylation
GO:0045780
IEA
Genome Projectpositive regulation of bone resorption
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048260
IDA, IGI
Genome Projectpositive regulation of receptor-mediated endocytosis
GO:0055072
IC, IEA
Genome Projectiron ion homeostasis
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0060395
IEA
Genome ProjectSMAD protein signal transduction
GO:0070371
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0071281
IGI
Genome Projectcellular response to iron ion
GO:0097460
IGI
Genome Projectferrous iron import into cell
GO:2000147
IEA
Genome Projectpositive regulation of cell motility

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008198
IDA
Genome Projectferrous iron binding
GO:0008199
IEA
Genome Projectferric iron binding
GO:0015091
IEA
Genome Projectferric iron transmembrane transporter activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:1990459
IPI
TAS
Genome Projecttransferrin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
TAS, NAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005768
IEA
Genome Projectendosome
GO:0005769
IDA
Genome Projectearly endosome
GO:0005770
IDA
Genome Projectlate endosome
GO:0005905
IDA
Genome Projectcoated pit
GO:0009925
IDA
Genome Projectbasal plasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0010008
TAS
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030139
IDA
IEA
Genome Projectendocytic vesicle
GO:0031232
IGI
Genome Projectextrinsic component of external side of plasma membrane
GO:0031982
IDA
Genome Projectvesicle
GO:0034774
TAS
Genome Projectsecretory granule lumen
GO:0045178
IDA
Genome Projectbasal part of cell
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0055037
IDA
Genome Projectrecycling endosome
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0072562
IDA
Genome Projectblood microparticle
GO:1990712
IDA
Genome ProjectHFE-transferrin receptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001156Transferrin-like domain
IPR016357Transferrin
IPR018195Transferrin family, iron binding site
IPR030685Serotransferrin, mammalian

No MapMan annotations defined for this gene.