Gene: ENSG00000091140 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000091140
Transcript Identifier
ENST00000417551
Gene Type
Coding gene
Location
7 : 107891251-107919259 : positive

Family Information

Homologous gene family
HOM03P000136
(220 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000812
(43 genes in 39 species)
specific family

Descriptions

gene_descr
dihydrolipoamide dehydrogenase

Identifiers

Type Value
pidENSP00000390667
HGNC2898
UniprotP09622
UniprotA0A024R713

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006086
IEA
Genome Projectacetyl-CoA biosynthetic process from pyruvate
GO:0006103
IEA
Genome Project2-oxoglutarate metabolic process
GO:0006120
IEA
Genome Projectmitochondrial electron transport, NADH to ubiquinone
GO:0006508
IEA
Genome Projectproteolysis
GO:0007369
IEA
Genome Projectgastrulation
GO:0007568
IEA
Genome Projectaging
GO:0009106
IEA
Genome Projectlipoate metabolic process
GO:0042391
IEA
Genome Projectregulation of membrane potential
GO:0045454
IEA
Genome Projectcell redox homeostasis
GO:0048240
IEA
Genome Projectsperm capacitation
GO:0051068
IEA
Genome Projectdihydrolipoamide metabolic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0006090
TAS
Genome Projectpyruvate metabolic process
GO:0006099
TAS
Genome Projecttricarboxylic acid cycle
GO:0006554
TAS
Genome Projectlysine catabolic process
GO:0009083
TAS
Genome Projectbranched-chain amino acid catabolic process
GO:0010510
TAS
Genome Projectregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004148
TAS, IEA
Genome Projectdihydrolipoyl dehydrogenase activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016668
IEA
Genome Projectoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0043544
IEA
Genome Projectlipoamide binding
GO:0050660
IEA
Genome Projectflavin adenine dinucleotide binding
GO:0051287
IEA
Genome ProjectNAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
TAS, IEA
Genome Projectmitochondrion
GO:0005929
IEA
Genome Projectcilium
GO:0043159
IEA
Genome Projectacrosomal matrix
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0045252
IEA
Genome Projectoxoglutarate dehydrogenase complex
GO:0045254
IEA
Genome Projectpyruvate dehydrogenase complex
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005759
TAS, IEA
Genome Projectmitochondrial matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004099Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPR006258Dihydrolipoamide dehydrogenase
IPR012999Pyridine nucleotide-disulphide oxidoreductase, class I, active site
IPR016156FAD/NAD-linked reductase, dimerisation domain
IPR023753FAD/NAD(P)-binding domain

No MapMan annotations defined for this gene.