Gene: ENSG00000088986 (Homo sapiens)

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Gene Identifier
ENSG00000088986
Transcript Identifier
ENST00000549989
Gene Type
Coding gene
Location
12 : 120496422-120498210 : positive

Family Information

Homologous gene family
HOM03P000340
(124 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P069306
(2 genes in 2 species)
specific family

Descriptions

gene_descr
dynein, light chain, LC8-type 1

Identifiers

Type Value
pidENSP00000446614
HGNC15476
UniprotP63167
UniprotQ6FGH9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006810
IEA
Genome Projecttransport
GO:0006915
TAS, IEA
Genome Projectapoptotic process
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007017
IEA
Genome Projectmicrotubule-based process
GO:0007292
TAS
Genome Projectfemale gamete generation
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0016032
IEA
Genome Projectviral process
GO:0019886
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0021762
IEP
Genome Projectsubstantia nigra development
GO:0030036
TAS
Genome Projectactin cytoskeleton organization
GO:0035721
IEA
Genome Projectintraciliary retrograde transport
GO:0042326
IDA
Genome Projectnegative regulation of phosphorylation
GO:0060271
IEA
Genome Projectcilium morphogenesis
GO:0097193
TAS
Genome Projectintrinsic apoptotic signaling pathway
GO:1900740
TAS
Genome Projectpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003774
TAS, IEA
Genome Projectmotor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IEA
Genome Projectprotein C-terminus binding
GO:0019904
IEA
Genome Projectprotein domain specific binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000776
IDA
Genome Projectkinetochore
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005868
ISS
TAS
Genome Projectcytoplasmic dynein complex
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005875
IEA
Genome Projectmicrotubule associated complex
GO:0005886
TAS
Genome Projectplasma membrane
GO:0016020
IDA
Genome Projectmembrane
GO:0030286
IEA
Genome Projectdynein complex
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0072372
TAS
Genome Projectprimary cilium
GO:0072686
IDA
Genome Projectmitotic spindle
GO:0097542
TAS
Genome Projectciliary tip
GO:0008180
IDA
Genome ProjectCOP9 signalosome
GO:0005929
IEA
Genome Projectcilium

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001372Dynein light chain, type 1/2
IPR019763Dynein light chain, type 1/2, conserved site

No MapMan annotations defined for this gene.