Gene: ENSG00000088888 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000088888
Transcript Identifier
ENST00000428216
Gene Type
Coding gene
Location
20 : 3854625-3866147 : positive

Family Information

Homologous gene family
HOM03P041201
(2 genes in 2 species)
specific family

Descriptions

gene_descr
mitochondrial antiviral signaling protein

Identifiers

Type Value
pidENSP00000401980
HGNC29233
UniprotQ7Z434

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001934
IDA
Genome Projectpositive regulation of protein phosphorylation
GO:0002218
IMP
Genome Projectactivation of innate immune response
GO:0002230
IDA, IMP
Genome Projectpositive regulation of defense response to virus by host
GO:0002376
IEA
Genome Projectimmune system process
GO:0007165
IMP
Genome Projectsignal transduction
GO:0016032
IEA
Genome Projectviral process
GO:0032480
TAS
Genome Projectnegative regulation of type I interferon production
GO:0032481
IEA
Genome Projectpositive regulation of type I interferon production
GO:0032727
IDA, IMP
Genome Projectpositive regulation of interferon-alpha production
GO:0032728
IDA, IMP
Genome Projectpositive regulation of interferon-beta production
GO:0032757
IDA
Genome Projectpositive regulation of interleukin-8 production
GO:0032760
IDA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0033160
IDA
Genome Projectpositive regulation of protein import into nucleus, translocation
GO:0039529
IEA
Genome ProjectRIG-I signaling pathway
GO:0042742
IMP
Genome Projectdefense response to bacterium
GO:0042993
IDA
Genome Projectpositive regulation of transcription factor import into nucleus
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045071
IDA
Genome Projectnegative regulation of viral genome replication
GO:0045087
IMP
TAS, IEA
Genome Projectinnate immune response
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051607
IDA
IEA
Genome Projectdefense response to virus
GO:0060340
IDA
Genome Projectpositive regulation of type I interferon-mediated signaling pathway
GO:0071360
IMP
Genome Projectcellular response to exogenous dsRNA
GO:0071651
IDA
Genome Projectpositive regulation of chemokine (C-C motif) ligand 5 production
GO:0071660
IDA
Genome Projectpositive regulation of IP-10 production
GO:1900063
IMP
Genome Projectregulation of peroxisome organization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IMP
IEA
Genome Projectsignal transducer activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0050700
IPI
Genome ProjectCARD domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005741
IDA
TAS, IEA
Genome Projectmitochondrial outer membrane
GO:0005777
IEA
Genome Projectperoxisome
GO:0005778
IDA
Genome Projectperoxisomal membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031966
IDA
Genome Projectmitochondrial membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR026148Mitochondrial antiviral-signalling protein
IPR031964Caspase recruitment domain

No MapMan annotations defined for this gene.