Gene: ENSG00000087470 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000087470
Transcript Identifier
ENST00000553257
Gene Type
Coding gene
Location
12 : 32679364-32743410 : positive

Family Information

Homologous gene family
HOM03P000185
(176 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000310
(55 genes in 38 species)
specific family

Descriptions

gene_descr
dynamin 1-like

Identifiers

Type Value
pidENSP00000449089
HGNC2973
UniprotO00429

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000266
IDA, IMP
IEA
Genome Projectmitochondrial fission
GO:0001836
IMP
Genome Projectrelease of cytochrome c from mitochondria
GO:0003374
IDA
Genome Projectdynamin polymerization involved in mitochondrial fission
GO:0006897
IEA
Genome Projectendocytosis
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006921
TAS
Genome Projectcellular component disassembly involved in execution phase of apoptosis
GO:0008152
IEA
Genome Projectmetabolic process
GO:0010821
IMP
Genome Projectregulation of mitochondrion organization
GO:0012501
TAS, IEA
Genome Projectprogrammed cell death
GO:0016559
IDA, IMP
IEA
Genome Projectperoxisome fission
GO:0032459
IDA
Genome Projectregulation of protein oligomerization
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0043653
IMP
Genome Projectmitochondrial fragmentation involved in apoptotic process
GO:0050714
IDA
Genome Projectpositive regulation of protein secretion
GO:0051289
IDA
Genome Projectprotein homotetramerization
GO:0060047
IEA
Genome Projectheart contraction
GO:0061025
IDA
Genome Projectmembrane fusion
GO:0070266
IMP
Genome Projectnecroptotic process
GO:0070584
IMP
Genome Projectmitochondrion morphogenesis
GO:0070585
IEA
Genome Projectprotein localization to mitochondrion
GO:0090141
IMP
TAS
Genome Projectpositive regulation of mitochondrial fission
GO:0090149
IDA
Genome Projectmitochondrial membrane fission
GO:0090200
IMP
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:1900063
IMP
Genome Projectregulation of peroxisome organization
GO:1903146
IGI
Genome Projectregulation of mitophagy
GO:1903578
IEA
Genome Projectregulation of ATP metabolic process
GO:2001244
IMP
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003924
IDA
IEA
Genome ProjectGTPase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0008289
IEA
Genome Projectlipid binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005741
IDA
TAS, IEA
Genome Projectmitochondrial outer membrane
GO:0005777
IDA, IMP
IEA
Genome Projectperoxisome
GO:0005794
IDA
IEA
Genome ProjectGolgi apparatus
GO:0005829
IDA
TAS, IEA
Genome Projectcytosol
GO:0005874
IDA
Genome Projectmicrotubule
GO:0005903
IEA
Genome Projectbrush border
GO:0005905
IEA
Genome Projectcoated pit
GO:0012505
IEA
Genome Projectendomembrane system
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030672
IEA
Genome Projectsynaptic vesicle membrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043231
IDA
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043234
IDA
Genome Projectprotein complex
GO:0045202
IEA
Genome Projectsynapse
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000375Dynamin central domain
IPR001401Dynamin, GTPase domain
IPR003130Dynamin GTPase effector
IPR019762Dynamin, GTPase region, conserved site
IPR020850GTPase effector domain
IPR022812Dynamin superfamily
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR030381Dynamin-type guanine nucleotide-binding (G) domain
IPR030556Dynamin-1-like protein

No MapMan annotations defined for this gene.