Gene: ENSG00000087085 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000087085
Transcript Identifier
ENST00000411582
Gene Type
Coding gene
Location
7 : 100890958-100894232 : negative

Family Information

Homologous gene family
HOM03P000191
(174 genes in 16 species)
specific family
Orthologous gene family
ORTHO03P008281
(10 genes in 5 species)
specific family

Descriptions

gene_descr
acetylcholinesterase (Yt blood group)

Identifiers

Type Value
pidENSP00000404865
HGNC108
UniprotP22303

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001507
NAS
Genome Projectacetylcholine catabolic process in synaptic cleft
GO:0001919
IEA
Genome Projectregulation of receptor recycling
GO:0002076
IEP
Genome Projectosteoblast development
GO:0006260
TAS
Genome ProjectDNA replication
GO:0006581
IDA
Genome Projectacetylcholine catabolic process
GO:0006644
TAS
Genome Projectphospholipid metabolic process
GO:0006656
TAS
Genome Projectphosphatidylcholine biosynthetic process
GO:0007155
IDA
TAS
Genome Projectcell adhesion
GO:0007268
IBA
TAS
Genome Projectsynaptic transmission
GO:0007399
TAS
Genome Projectnervous system development
GO:0007416
TAS
Genome Projectsynapse assembly
GO:0007517
TAS
Genome Projectmuscle organ development
GO:0008283
TAS
Genome Projectcell proliferation
GO:0009611
TAS
Genome Projectresponse to wounding
GO:0031623
IEA
Genome Projectreceptor internalization
GO:0032223
IC
Genome Projectnegative regulation of synaptic transmission, cholinergic
GO:0042135
IEA
Genome Projectneurotransmitter catabolic process
GO:0042136
TAS
Genome Projectneurotransmitter biosynthetic process
GO:0042982
TAS
Genome Projectamyloid precursor protein metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045212
IEA
Genome Projectneurotransmitter receptor biosynthetic process
GO:0046474
TAS
Genome Projectglycerophospholipid biosynthetic process
GO:0050714
TAS
Genome Projectpositive regulation of protein secretion
GO:0051262
IEA
Genome Projectprotein tetramerization
GO:0060041
IEA
Genome Projectretina development in camera-type eye

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001540
TAS
Genome Projectbeta-amyloid binding
GO:0003990
IDA, IMP
IEA
Genome Projectacetylcholinesterase activity
GO:0004104
IDA
IEA
Genome Projectcholinesterase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005518
IDA
Genome Projectcollagen binding
GO:0016787
IDA
IEA
Genome Projecthydrolase activity
GO:0017171
IDA
Genome Projectserine hydrolase activity
GO:0042166
IDA
NAS
Genome Projectacetylcholine binding
GO:0042803
IPI
NAS
Genome Projectprotein homodimerization activity
GO:0043236
IDA
Genome Projectlaminin binding
GO:0043621
IEA
Genome Projectprotein self-association
GO:0052689
IEA
Genome Projectcarboxylic ester hydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
TAS, IEA
Genome Projectextracellular region
GO:0005605
NAS, IEA
Genome Projectbasal lamina
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005634
IEA
Genome Projectnucleus
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0031225
IEA
Genome Projectanchored component of membrane
GO:0031594
IBA
IEA
Genome Projectneuromuscular junction
GO:0043083
NAS
Genome Projectsynaptic cleft
GO:0045202
IDA
IEA
Genome Projectsynapse
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000997Cholinesterase
IPR002018Carboxylesterase, type B
IPR014788Acetylcholinesterase, tetramerisation domain
IPR019819Carboxylesterase type B, conserved site
IPR019826Carboxylesterase type B, active site
IPR029058Alpha/Beta hydrolase fold

No MapMan annotations defined for this gene.