Gene: ENSG00000087053 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000087053
Transcript Identifier
ENST00000346299
Gene Type
Coding gene
Location
11 : 95835290-95923954 : negative

Family Information

Homologous gene family
HOM03P000658
(81 genes in 19 species)
specific family
Orthologous gene family
ORTHO03P003951
(21 genes in 13 species)
specific family

Descriptions

gene_descr
myotubularin related protein 2

Identifiers

Type Value
pidENSP00000345752
HGNC7450
UniprotQ13614

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002091
ISS
IEA
Genome Projectnegative regulation of receptor internalization
GO:0006470
NAS
Genome Projectprotein dephosphorylation
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006644
TAS
Genome Projectphospholipid metabolic process
GO:0006661
TAS
Genome Projectphosphatidylinositol biosynthetic process
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0031642
IEA
Genome Projectnegative regulation of myelination
GO:0032288
IEA
Genome Projectmyelin assembly
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045806
ISS
IEA
Genome Projectnegative regulation of endocytosis
GO:0046488
IEA
Genome Projectphosphatidylinositol metabolic process
GO:0046855
IEA
Genome Projectinositol phosphate dephosphorylation
GO:0046856
IDA
IEA
Genome Projectphosphatidylinositol dephosphorylation
GO:0048666
IEA
Genome Projectneuron development
GO:0051262
IEA
Genome Projectprotein tetramerization
GO:0090394
ISS
IEA
Genome Projectnegative regulation of excitatory postsynaptic potential
GO:0097062
ISS
IEA
Genome Projectdendritic spine maintenance
GO:2000643
ISS
IEA
Genome Projectpositive regulation of early endosome to late endosome transport
GO:2000645
ISS
IEA
Genome Projectnegative regulation of receptor catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004438
IDA
IEA
Genome Projectphosphatidylinositol-3-phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008138
NAS
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0052629
IDA
IEA
Genome Projectphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO:0052866
IEA
Genome Projectphosphatidylinositol phosphate phosphatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005774
IEA
Genome Projectvacuolar membrane
GO:0005829
IDA
ISS
TAS, IEA
Genome Projectcytosol
GO:0008021
ISS
IEA
Genome Projectsynaptic vesicle
GO:0016020
IEA
Genome Projectmembrane
GO:0030424
ISS
IEA
Genome Projectaxon
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0031901
IEA
Genome Projectearly endosome membrane
GO:0043197
ISS
IEA
Genome Projectdendritic spine
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0097060
ISS
IEA
Genome Projectsynaptic membrane
GO:0097481
ISS
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000387Tyrosine specific protein phosphatases domain
IPR004182GRAM domain
IPR010569Myotubularin-like phosphatase domain
IPR011993PH domain-like
IPR016130Protein-tyrosine phosphatase, active site
IPR029021Protein-tyrosine phosphatase-like
IPR030564Myotubularin family

No MapMan annotations defined for this gene.