Gene: ENSG00000086758 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000086758
Transcript Identifier
ENST00000262854
Gene Type
Coding gene
Location
X : 53533309-53654107 : negative

Family Information

Homologous gene family
HOM03P000060
(418 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000839
(43 genes in 34 species)
specific family

Descriptions

gene_descr
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase

Identifiers

Type Value
pidENSP00000262854
HGNC30892
UniprotQ7Z6Z7
UniprotA0A024R9W5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008152
IEA
Genome Projectmetabolic process
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0000209
IDA
Genome Projectprotein polyubiquitination
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006284
IMP
Genome Projectbase-excision repair
GO:0006513
IDA
Genome Projectprotein monoubiquitination
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0016574
IDA
Genome Projecthistone ubiquitination
GO:0030154
IEA
Genome Projectcell differentiation
GO:0042787
IBA
Genome Projectprotein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1903955
IMP
Genome Projectpositive regulation of protein targeting to mitochondrion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004842
IDA
IEA
Genome Projectubiquitin-protein transferase activity
GO:0016874
IEA
Genome Projectligase activity
GO:0003677
ISS
IEA
Genome ProjectDNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0016020
IDA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000569HECT domain
IPR004170WWE domain
IPR009060UBA-like
IPR010309E3 ubiquitin ligase, domain of unknown function DUF908
IPR010314E3 ubiquitin ligase, domain of unknown function DUF913
IPR015940Ubiquitin-associated domain
IPR016024Armadillo-type fold
IPR025527Domain of unknown function DUF4414

No MapMan annotations defined for this gene.