Gene: ENSG00000085224 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000085224
Transcript Identifier
ENST00000373344
Gene Type
Coding gene
Location
X : 77508351-77786001 : negative

Family Information

Homologous gene family
HOM03P000018
(1093 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P008678
(10 genes in 10 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
alpha thalassemia/mental retardation syndrome X- linked

Identifiers

Type Value
pidENSP00000362441
HGNC886
UniprotP46100
UniprotA4LAA3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0010571
ISS
IEA
Genome Projectpositive regulation of nuclear cell cycle DNA replication
GO:0030330
ISS
IEA
Genome ProjectDNA damage response, signal transduction by p53 class mediator
GO:0030900
IEA
Genome Projectforebrain development
GO:0031297
ISS
IEA
Genome Projectreplication fork processing
GO:0032206
ISS
IEA
Genome Projectpositive regulation of telomere maintenance
GO:0035128
IEA
Genome Projectpost-embryonic forelimb morphogenesis
GO:0035264
IEA
Genome Projectmulticellular organism growth
GO:0060009
IEA
Genome ProjectSertoli cell development
GO:0072520
IEA
Genome Projectseminiferous tubule development
GO:0072711
ISS
IEA
Genome Projectcellular response to hydroxyurea
GO:1901581
ISS
IEA
Genome Projectnegative regulation of telomeric RNA transcription from RNA pol II promoter
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006306
TAS
Genome ProjectDNA methylation
GO:0006310
TAS
Genome ProjectDNA recombination
GO:0006334
IDA
Genome Projectnucleosome assembly
GO:0006336
IMP
Genome ProjectDNA replication-independent nucleosome assembly
GO:0006338
IDA
Genome Projectchromatin remodeling
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
TAS, IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0016568
IEA
Genome Projectchromatin modification
GO:0032508
TAS
Genome ProjectDNA duplex unwinding
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003682
IEA
Genome Projectchromatin binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003678
TAS
Genome ProjectDNA helicase activity
GO:0004386
TAS, IEA
Genome Projecthelicase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0015616
IDA
Genome ProjectDNA translocase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0035064
IDA
Genome Projectmethylated histone binding
GO:0042393
IDA
Genome Projecthistone binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070087
IPI
Genome Projectchromo shadow domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000228
IEA
Genome Projectnuclear chromosome
GO:0000792
IEA
Genome Projectheterochromatin
GO:0031933
ISS
IEA
Genome Projecttelomeric heterochromatin
GO:0000781
IEA
Genome Projectchromosome, telomeric region
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005694
IEA
Genome Projectchromosome
GO:0005720
TAS
Genome Projectnuclear heterochromatin
GO:0016605
IEA
Genome ProjectPML body
GO:0070603
IDA
Genome ProjectSWI/SNF superfamily-type complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000330SNF2-related, N-terminal domain
IPR001650Helicase, C-terminal
IPR001841Zinc finger, RING-type
IPR011011Zinc finger, FYVE/PHD-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR025766ADD domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.