Gene: ENSG00000084676 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000084676
Transcript Identifier
ENST00000348332
Gene Type
Coding gene
Location
2 : 24658678-24768391 : positive

Family Information

Homologous gene family
HOM03P012843
(6 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P063926
(2 genes in 2 species)
specific family

Descriptions

gene_descr
nuclear receptor coactivator 1

Identifiers

Type Value
pidENSP00000320940
HGNC7668
UniprotQ15788

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000435
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter by galactose
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
IDA
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007595
IEA
Genome Projectlactation
GO:0008206
TAS
Genome Projectbile acid metabolic process
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009725
IEA
Genome Projectresponse to hormone
GO:0015721
TAS
Genome Projectbile acid and bile salt transport
GO:0021549
IEA
Genome Projectcerebellum development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0021854
IEA
Genome Projecthypothalamus development
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0030521
NAS
Genome Projectandrogen receptor signaling pathway
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0032870
IBA
IEA
Genome Projectcellular response to hormone stimulus
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043967
IEA
Genome Projecthistone H4 acetylation
GO:0044255
TAS
Genome Projectcellular lipid metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0044849
IEA
Genome Projectestrous cycle
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045893
IDA
NAS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045925
IEA
Genome Projectpositive regulation of female receptivity
GO:0045944
IDA
NAS, IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0060179
IEA
Genome Projectmale mating behavior
GO:0060713
IEA
Genome Projectlabyrinthine layer morphogenesis
GO:2001038
IEA
Genome Projectregulation of cellular response to drug
GO:2001141
IEA
Genome Projectregulation of RNA biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001012
IEA
Genome ProjectRNA polymerase II regulatory region DNA binding
GO:0001105
NAS
Genome ProjectRNA polymerase II transcription coactivator activity
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003713
IDA
NAS, IEA
Genome Projecttranscription coactivator activity
GO:0004402
IEA
Genome Projecthistone acetyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
IEA
Genome Projecttransferase activity, transferring acyl groups
GO:0016922
IPI
IEA
Genome Projectligand-dependent nuclear receptor binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0030331
IEA
Genome Projectestrogen receptor binding
GO:0030374
IDA
IEA
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0033142
IEA
Genome Projectprogesterone receptor binding
GO:0035257
IDA
IEA
Genome Projectnuclear hormone receptor binding
GO:0042974
IEA
Genome Projectretinoic acid receptor binding
GO:0046965
IEA
Genome Projectretinoid X receptor binding
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0047485
IPI
Genome Projectprotein N-terminus binding
GO:0050681
NAS
Genome Projectandrogen receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IBA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm
GO:0043005
IEA
Genome Projectneuron projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000014PAS domain
IPR008955Nuclear receptor coactivator Src-1
IPR009110Nuclear receptor coactivator, interlocking
IPR010011Domain of unknown function DUF1518
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
IPR013767PAS fold
IPR014920Nuclear receptor coactivator, Ncoa-type, interlocking
IPR014935Steroid receptor coactivator

No MapMan annotations defined for this gene.