Gene: ENSG00000082701 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000082701
Transcript Identifier
ENST00000316626
Gene Type
Coding gene
Location
3 : 119826788-120093434 : negative

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000108
(79 genes in 38 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
glycogen synthase kinase 3 beta

Identifiers

Type Value
pidENSP00000324806
HGNC4617
UniprotP49841

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000320
IEA
Genome Projectre-entry into mitotic cell cycle
GO:0001837
IMP
Genome Projectepithelial to mesenchymal transition
GO:0001954
IMP
Genome Projectpositive regulation of cell-matrix adhesion
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0005977
IDA
IEA
Genome Projectglycogen metabolic process
GO:0006349
IEA
Genome Projectregulation of gene expression by genetic imprinting
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006611
IEA
Genome Projectprotein export from nucleus
GO:0006983
IDA
Genome ProjectER overload response
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007409
IEA
Genome Projectaxonogenesis
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007520
IEA
Genome Projectmyoblast fusion
GO:0007623
ISS
IEA
Genome Projectcircadian rhythm
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0009968
IEA
Genome Projectnegative regulation of signal transduction
GO:0010614
IEA
Genome Projectnegative regulation of cardiac muscle hypertrophy
GO:0010800
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010975
IEA
Genome Projectregulation of neuron projection development
GO:0010977
IEA
Genome Projectnegative regulation of neuron projection development
GO:0014043
IEA
Genome Projectnegative regulation of neuron maturation
GO:0014902
IEA
Genome Projectmyotube differentiation
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IEA
Genome Projectcell migration
GO:0018105
IDA
Genome Projectpeptidyl-serine phosphorylation
GO:0021766
IMP
Genome Projecthippocampus development
GO:0030154
IEA
Genome Projectcell differentiation
GO:0031333
IMP
Genome Projectnegative regulation of protein complex assembly
GO:0031334
IDA
Genome Projectpositive regulation of protein complex assembly
GO:0032091
IDA
Genome Projectnegative regulation of protein binding
GO:0032092
ISS
IEA
Genome Projectpositive regulation of protein binding
GO:0032436
IEA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032886
IMP
Genome Projectregulation of microtubule-based process
GO:0033138
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0034605
TAS
Genome Projectcellular response to heat
GO:0035372
IEA
Genome Projectprotein localization to microtubule
GO:0035556
IDA
Genome Projectintracellular signal transduction
GO:0036016
ISS
IEA
Genome Projectcellular response to interleukin-3
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043547
IMP
Genome Projectpositive regulation of GTPase activity
GO:0044027
IEA
Genome Projecthypermethylation of CpG island
GO:0044337
IEA
Genome Projectcanonical Wnt signaling pathway involved in positive regulation of apoptotic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045444
IEA
Genome Projectfat cell differentiation
GO:0045719
TAS
Genome Projectnegative regulation of glycogen biosynthetic process
GO:0045732
IC
Genome Projectpositive regulation of protein catabolic process
GO:0045773
IEA
Genome Projectpositive regulation of axon extension
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0046827
IDA
Genome Projectpositive regulation of protein export from nucleus
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0048015
TAS
Genome Projectphosphatidylinositol-mediated signaling
GO:0048511
IEA
Genome Projectrhythmic process
GO:0051534
IMP
Genome Projectnegative regulation of NFAT protein import into nucleus
GO:0060070
IDA
IC
Genome Projectcanonical Wnt signaling pathway
GO:0070059
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071109
IMP
Genome Projectsuperior temporal gyrus development
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0097192
ISS
IEA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:1900034
TAS
Genome Projectregulation of cellular response to heat
GO:1900181
ISS
Genome Projectnegative regulation of protein localization to nucleus
GO:1901030
ISS
IEA
Genome Projectpositive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:2000077
TAS
Genome Projectnegative regulation of type B pancreatic cell development
GO:2000466
TAS
Genome Projectnegative regulation of glycogen (starch) synthase activity
GO:2000738
IEA
Genome Projectpositive regulation of stem cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0001085
IPI
Genome ProjectRNA polymerase II transcription factor binding
GO:0002039
IDA
Genome Projectp53 binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISS
TAS, IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008013
IPI
Genome Projectbeta-catenin binding
GO:0016301
IDA
TAS, IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0034236
IPI
Genome Projectprotein kinase A catalytic subunit binding
GO:0050321
IDA
IEA
Genome Projecttau-protein kinase activity
GO:0051059
IPI
Genome ProjectNF-kappaB binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS, IEA
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0030426
IEA
Genome Projectgrowth cone
GO:0030529
IEA
Genome Projectintracellular ribonucleoprotein complex
GO:0030877
IDA
TAS
Genome Projectbeta-catenin destruction complex
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043198
IEA
Genome Projectdendritic shaft
GO:0043227
IEA
Genome Projectmembrane-bounded organelle
GO:0044297
IEA
Genome Projectcell body
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097481
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.