Gene: ENSG00000081237 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000081237
Transcript Identifier
ENST00000442510
Gene Type
Coding gene
Location
1 : 198639269-198756181 : positive

Family Information

Homologous gene family
HOM03P000197
(172 genes in 24 species)
specific family
Orthologous gene family
ORTHO03P032341
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
protein tyrosine phosphatase, receptor type, C

Identifiers

Type Value
pidENSP00000411355
HGNC9666
UniprotA0A0A0MT22

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IEA
Genome Projectactivation of MAPK activity
GO:0001916
IEA
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002711
IEA
Genome Projectpositive regulation of T cell mediated immunity
GO:0002923
IEA
Genome Projectregulation of humoral immune response mediated by circulating immunoglobulin
GO:0002925
IEA
Genome Projectpositive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0006470
IEA
Genome Projectprotein dephosphorylation
GO:0007159
IEA
Genome Projectleukocyte cell-cell adhesion
GO:0010332
IEA
Genome Projectresponse to gamma radiation
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0030183
IEA
Genome ProjectB cell differentiation
GO:0031953
IEA
Genome Projectnegative regulation of protein autophosphorylation
GO:0034113
IEA
Genome Projectheterotypic cell-cell adhesion
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0042098
IEA
Genome ProjectT cell proliferation
GO:0043410
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0045059
IEA
Genome Projectpositive thymic T cell selection
GO:0045060
IEA
Genome Projectnegative thymic T cell selection
GO:0045577
IEA
Genome Projectregulation of B cell differentiation
GO:0045582
IEA
Genome Projectpositive regulation of T cell differentiation
GO:0045588
IEA
Genome Projectpositive regulation of gamma-delta T cell differentiation
GO:0046641
IEA
Genome Projectpositive regulation of alpha-beta T cell proliferation
GO:0048304
IEA
Genome Projectpositive regulation of isotype switching to IgG isotypes
GO:0050732
IEA
Genome Projectnegative regulation of peptidyl-tyrosine phosphorylation
GO:0050852
IEA
Genome ProjectT cell receptor signaling pathway
GO:0050853
IEA
Genome ProjectB cell receptor signaling pathway
GO:0050855
IEA
Genome Projectregulation of B cell receptor signaling pathway
GO:0051607
IEA
Genome Projectdefense response to virus
GO:2001236
IEA
Genome Projectregulation of extrinsic apoptotic signaling pathway
GO:2001238
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0008201
IEA
Genome Projectheparin binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0043395
IEA
Genome Projectheparan sulfate proteoglycan binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0071944
IEA
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000242PTP type protein phosphatase
IPR000387Tyrosine specific protein phosphatases domain
IPR003595Protein-tyrosine phosphatase, catalytic
IPR003961Fibronectin type III
IPR013783Immunoglobulin-like fold
IPR016130Protein-tyrosine phosphatase, active site
IPR016335Receptor-type tyrosine-protein phosphatase C
IPR024739Protein tyrosine phosphatase, receptor type, N-terminal
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.