Gene: ENSG00000080644 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000080644
Transcript Identifier
ENST00000326828
Gene Type
Coding gene
Location
15 : 78596604-78620794 : negative

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P006938
(12 genes in 5 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
cholinergic receptor, nicotinic, alpha 3 (neuronal)

Identifiers

Type Value
pidENSP00000315602
HGNC1957
UniprotP32297

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0006811
NAS, IEA
Genome Projection transport
GO:0006812
IDA
TAS, IEA
Genome Projectcation transport
GO:0006940
ISS
Genome Projectregulation of smooth muscle contraction
GO:0007165
IDA
Genome Projectsignal transduction
GO:0007171
ISS
Genome Projectactivation of transmembrane receptor protein tyrosine kinase activity
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0007271
ISS, IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007399
IMP
Genome Projectnervous system development
GO:0007507
IEA
Genome Projectheart development
GO:0007626
ISS
Genome Projectlocomotory behavior
GO:0010035
IEA
Genome Projectresponse to inorganic substance
GO:0014056
ISS
Genome Projectregulation of acetylcholine secretion, neurotransmission
GO:0034220
TAS, IEA
Genome Projection transmembrane transport
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0035095
IMP
Genome Projectbehavioral response to nicotine
GO:0042391
ISS, IBA
Genome Projectregulation of membrane potential
GO:0042493
IEA
Genome Projectresponse to drug
GO:0048814
ISS
Genome Projectregulation of dendrite morphogenesis
GO:0050877
IBA
Genome Projectneurological system process
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0060079
ISS
Genome Projectexcitatory postsynaptic potential
GO:0060084
IMP
Genome Projectsynaptic transmission involved in micturition
GO:0098655
IDA
TAS, IEA
Genome Projectcation transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004889
IDA
TAS, IEA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0008144
IEA
Genome Projectdrug binding
GO:0015276
TAS
Genome Projectligand-gated ion channel activity
GO:0015464
IDA
IEA
Genome Projectacetylcholine receptor activity
GO:0042166
IBA
IC, IEA
Genome Projectacetylcholine binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005892
IDA
Genome Projectacetylcholine-gated channel complex
GO:0014069
ISS
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
NAS, IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
ISS
IEA
Genome Projectdendrite
GO:0043005
IBA
Genome Projectneuron projection
GO:0043025
ISS
IEA
Genome Projectneuronal cell body
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002394Nicotinic acetylcholine receptor
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.