Gene: ENSG00000078900 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000078900
Transcript Identifier
ENST00000378295
Gene Type
Coding gene
Location
1 : 3682366-3733079 : positive

Family Information

Homologous gene family
HOM03P014610
(6 genes in 3 species)
specific family

Descriptions

gene_descr
tumor protein p73

Identifiers

Type Value
pidENSP00000367545
HGNC12003
UniprotO15350
UniprotA0A024R4C3

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IEA
Genome Projectactivation of MAPK activity
GO:0001822
IEA
Genome Projectkidney development
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007050
IEA
Genome Projectcell cycle arrest
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0010243
IEA
Genome Projectresponse to organonitrogen compound
GO:0021766
IEA
Genome Projecthippocampus development
GO:0030900
IEA
Genome Projectforebrain development
GO:0033326
IEA
Genome Projectcerebrospinal fluid secretion
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043523
IEA
Genome Projectregulation of neuron apoptotic process
GO:0043524
IBA
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045793
IEA
Genome Projectpositive regulation of cell size
GO:0048546
IEA
Genome Projectdigestive tract morphogenesis
GO:0048666
IEA
Genome Projectneuron development
GO:0048714
IEA
Genome Projectpositive regulation of oligodendrocyte differentiation
GO:0051262
IEA
Genome Projectprotein tetramerization
GO:1902167
IEA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2001235
IEA
Genome Projectpositive regulation of apoptotic signaling pathway
GO:0000122
IBA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006298
TAS
Genome Projectmismatch repair
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006974
IDA
Genome Projectcellular response to DNA damage stimulus
GO:0006978
IBA
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007049
IEA
Genome Projectcell cycle
GO:0007346
IMP
Genome Projectregulation of mitotic cell cycle
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0008630
TAS
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0010165
IBA
Genome Projectresponse to X-ray
GO:0010332
IBA
Genome Projectresponse to gamma radiation
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0016032
IEA
Genome Projectviral process
GO:0031571
IBA
Genome Projectmitotic G1 DNA damage checkpoint
GO:0034644
IBA
Genome Projectcellular response to UV
GO:0042771
IDA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043508
IBA
Genome Projectnegative regulation of JUN kinase activity
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0060044
IMP
Genome Projectnegative regulation of cardiac muscle cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002039
IBA
IEA
Genome Projectp53 binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IDA
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981
IDA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682
IBA
Genome Projectchromatin binding
GO:0003684
IBA
Genome Projectdamaged DNA binding
GO:0003690
IBA
Genome Projectdouble-stranded DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
IBA
IEA
Genome Projectchromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005667
IBA
Genome Projecttranscription factor complex
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005829
IBA
Genome Projectcytosol
GO:0030054
IDA
Genome Projectcell junction
GO:0043231
IDA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001660Sterile alpha motif domain
IPR002117p53 tumour suppressor family
IPR008967p53-like transcription factor, DNA-binding
IPR010991p53, tetramerisation domain
IPR011615p53, DNA-binding domain
IPR012346p53/RUNT-type transcription factor, DNA-binding domain
IPR013761Sterile alpha motif/pointed domain
IPR032646Tumour protein p73

No MapMan annotations defined for this gene.