Gene: ENSG00000078140 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000078140
Transcript Identifier
ENST00000261427
Gene Type
Coding gene
Location
4 : 39698328-39778434 : positive

Family Information

Homologous gene family
HOM03P000028
(788 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001011
(41 genes in 35 species)
specific family

Descriptions

gene_descr
ubiquitin-conjugating enzyme E2K

Identifiers

Type Value
pidENSP00000261427
HGNC4914
UniprotP61086

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006511
TAS
Genome Projectubiquitin-dependent protein catabolic process
GO:0010800
IDA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010994
IDA
Genome Projectfree ubiquitin chain polymerization
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0032434
IEA
Genome Projectregulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035458
IMP
Genome Projectcellular response to interferon-beta
GO:0043161
IBA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0060340
IMP
Genome Projectpositive regulation of type I interferon-mediated signaling pathway
GO:0070059
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070936
IDA
Genome Projectprotein K48-linked ubiquitination

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004842
IDA
TAS
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016874
IEA
Genome Projectligase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0034450
IDA
Genome Projectubiquitin-ubiquitin ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0015629
IDA
Genome Projectactin cytoskeleton
GO:0032433
IEA
Genome Projectfilopodium tip
GO:0045111
IDA
Genome Projectintermediate filament cytoskeleton
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000608Ubiquitin-conjugating enzyme E2
IPR009060UBA-like
IPR015940Ubiquitin-associated domain
IPR016135Ubiquitin-conjugating enzyme/RWD-like
IPR023313Ubiquitin-conjugating enzyme, active site

No MapMan annotations defined for this gene.