Gene: ENSG00000074319 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000074319
Transcript Identifier
ENST00000251968
Gene Type
Coding gene
Location
11 : 18480546-18526816 : negative

Family Information

Homologous gene family
HOM03P002002
(42 genes in 31 species)
specific family
Orthologous gene family
ORTHO03P002019
(33 genes in 28 species)
specific family

Descriptions

gene_descr
tumor susceptibility 101

Identifiers

Type Value
pidENSP00000251968
HGNC15971
UniprotQ99816

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001558
IEA
Genome Projectregulation of cell growth
GO:0006464
IEA
Genome Projectcellular protein modification process
GO:0006513
IEA
Genome Projectprotein monoubiquitination
GO:0006810
IEA
Genome Projecttransport
GO:0007049
IEA
Genome Projectcell cycle
GO:0007050
IEA
Genome Projectcell cycle arrest
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008333
IEA
Genome Projectendosome to lysosome transport
GO:0015031
IEA
Genome Projectprotein transport
GO:0016032
TAS, IEA
Genome Projectviral process
GO:0016197
TAS
Genome Projectendosomal transport
GO:0019058
TAS
Genome Projectviral life cycle
GO:0019068
TAS
Genome Projectvirion assembly
GO:0019082
TAS
Genome Projectviral protein processing
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030216
IEA
Genome Projectkeratinocyte differentiation
GO:0040008
IEA
Genome Projectregulation of growth
GO:0043162
IDA, IMP
IC
Genome Projectubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043405
IMP
Genome Projectregulation of MAP kinase activity
GO:0045892
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046755
IMP
ISS
Genome Projectviral budding
GO:0048524
IMP
Genome Projectpositive regulation of viral process
GO:0051301
IEA
Genome Projectcell division
GO:0061024
TAS
Genome Projectmembrane organization
GO:0075733
TAS
Genome Projectintracellular transport of virus
GO:1902188
IMP
Genome Projectpositive regulation of viral release from host cell
GO:1903506
IEA
Genome Projectregulation of nucleic acid-templated transcription
GO:1903543
IMP
Genome Projectpositive regulation of exosomal secretion
GO:1903551
IMP
Genome Projectregulation of extracellular exosome assembly
GO:1903772
IMP
Genome Projectregulation of viral budding via host ESCRT complex
GO:1903774
IMP
Genome Projectpositive regulation of viral budding via host ESCRT complex
GO:2000397
IEA
Genome Projectpositive regulation of ubiquitin-dependent endocytosis
GO:1902186
IMP
Genome Projectregulation of viral release from host cell

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
TAS
Genome ProjectDNA binding
GO:0003714
TAS, IEA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0030374
IEA
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0042803
IPI
Genome Projectprotein homodimerization activity
GO:0043130
IDA
TAS
Genome Projectubiquitin binding
GO:0046790
IDA
Genome Projectvirion binding
GO:0048306
IPI
Genome Projectcalcium-dependent protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000813
IDA
Genome ProjectESCRT I complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005730
IDA
Genome Projectnucleolus
GO:0005737
IDA
ISS
IEA
Genome Projectcytoplasm
GO:0005768
IDA
IEA
Genome Projectendosome
GO:0005769
IDA
Genome Projectearly endosome
GO:0005770
IMP
Genome Projectlate endosome
GO:0005771
TAS
Genome Projectmultivesicular body
GO:0005886
IDA
Genome Projectplasma membrane
GO:0010008
TAS, IEA
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031902
IEA
Genome Projectlate endosome membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR008883Ubiquitin E2 variant, N-terminal
IPR016135Ubiquitin-conjugating enzyme/RWD-like
IPR017916Steadiness box (SB) domain

No MapMan annotations defined for this gene.