Gene: ENSG00000072518 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000072518
Transcript Identifier
ENST00000402010
Gene Type
Coding gene
Location
11 : 63839507-63909237 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P009357
(9 genes in 3 species)
specific family

Descriptions

gene_descr
MAP/microtubule affinity-regulating kinase 2

Identifiers

Type Value
pidENSP00000385751
HGNC3332
UniprotQ7KZI7

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000422
NAS
Genome Projectmitophagy
GO:0001764
ISS
Genome Projectneuron migration
GO:0006468
IDA
TAS, NAS, IEA
Genome Projectprotein phosphorylation
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0010976
IDA
Genome Projectpositive regulation of neuron projection development
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018107
TAS
Genome Projectpeptidyl-threonine phosphorylation
GO:0030010
IDA
TAS
Genome Projectestablishment of cell polarity
GO:0030154
IEA
Genome Projectcell differentiation
GO:0032147
TAS
Genome Projectactivation of protein kinase activity
GO:0035556
IDA
Genome Projectintracellular signal transduction
GO:0045197
IDA
Genome Projectestablishment or maintenance of epithelial cell apical/basal polarity
GO:0046777
ISS
Genome Projectprotein autophosphorylation
GO:0050770
IMP
Genome Projectregulation of axonogenesis
GO:0051493
ISS
Genome Projectregulation of cytoskeleton organization
GO:0051646
NAS
Genome Projectmitochondrion localization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
IDA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
TAS, NAS, IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0008289
IEA
Genome Projectlipid binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0030295
TAS
Genome Projectprotein kinase activator activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050321
ISS
IEA
Genome Projecttau-protein kinase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
NAS
Genome Projectmitochondrion
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005884
IDA
Genome Projectactin filament
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IMP
IEA
Genome Projectmembrane
GO:0016328
IDA
IEA
Genome Projectlateral plasma membrane
GO:0045180
IEA
Genome Projectbasal cortex
GO:0097427
IDA
Genome Projectmicrotubule bundle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001772Kinase associated domain 1 (KA1)
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR015940Ubiquitin-associated domain
IPR017441Protein kinase, ATP binding site
IPR028375KA1 domain/Ssp2, C-terminal

No MapMan annotations defined for this gene.