Gene: ENSG00000072310 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000072310
Transcript Identifier
ENST00000355815
Gene Type
Coding gene
Location
17 : 17812622-17836817 : negative

Family Information

Homologous gene family
HOM03P008161
(10 genes in 6 species)
specific family

Descriptions

gene_descr
sterol regulatory element binding transcription factor 1

Identifiers

Type Value
pidENSP00000348069
HGNC11289
UniprotP36956

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0003062
IEA
Genome Projectregulation of heart rate by chemical signal
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006629
TAS, IEA
Genome Projectlipid metabolic process
GO:0007568
IEA
Genome Projectaging
GO:0007623
TAS, IEA
Genome Projectcircadian rhythm
GO:0008202
IEA
Genome Projectsteroid metabolic process
GO:0008203
IEA
Genome Projectcholesterol metabolic process
GO:0008286
IEA
Genome Projectinsulin receptor signaling pathway
GO:0008610
ISS
IEA
Genome Projectlipid biosynthetic process
GO:0009267
ISS
IEA
Genome Projectcellular response to starvation
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010867
ISS
IEA
Genome Projectpositive regulation of triglyceride biosynthetic process
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019217
IEA
Genome Projectregulation of fatty acid metabolic process
GO:0030324
IEA
Genome Projectlung development
GO:0031065
IEA
Genome Projectpositive regulation of histone deacetylation
GO:0031647
IMP
Genome Projectregulation of protein stability
GO:0032094
IEA
Genome Projectresponse to food
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0033762
IEA
Genome Projectresponse to glucagon
GO:0033993
IEA
Genome Projectresponse to lipid
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045542
IEA
Genome Projectpositive regulation of cholesterol biosynthetic process
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046676
IEA
Genome Projectnegative regulation of insulin secretion
GO:0050796
IEA
Genome Projectregulation of insulin secretion
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0070542
IEA
Genome Projectresponse to fatty acid
GO:0071398
IEA
Genome Projectcellular response to fatty acid
GO:1903146
IMP
Genome Projectregulation of mitophagy
GO:1903214
IMP
Genome Projectregulation of protein targeting to mitochondrion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
ISS
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0032810
IDA
Genome Projectsterol response element binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046983
IEA
Genome Projectprotein dimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
TAS, IEA
Genome ProjectGolgi membrane
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005635
TAS
Genome Projectnuclear envelope
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005789
TAS, IEA
Genome Projectendoplasmic reticulum membrane
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
TAS
Genome Projectcytosol
GO:0012507
IEA
Genome ProjectER to Golgi transport vesicle membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043234
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain

No MapMan annotations defined for this gene.