Gene: ENSG00000072062 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000072062
Transcript Identifier
ENST00000308677
Gene Type
Coding gene
Location
19 : 14093112-14117547 : negative

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000331
(54 genes in 23 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
protein kinase, cAMP-dependent, catalytic, alpha

Identifiers

Type Value
pidENSP00000309591
HGNC9380
UniprotP17612
UniprotA0A024R7J0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001707
IEA
Genome Projectmesoderm formation
GO:0001843
IEA
Genome Projectneural tube closure
GO:0006468
NAS, IEA
Genome Projectprotein phosphorylation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018105
IDA
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0018107
IEA
Genome Projectpeptidyl-threonine phosphorylation
GO:0043457
IEA
Genome Projectregulation of cellular respiration
GO:0046777
IEA
Genome Projectprotein autophosphorylation
GO:0046827
IEA
Genome Projectpositive regulation of protein export from nucleus
GO:0048240
ISS
IEA
Genome Projectsperm capacitation
GO:0050804
IEA
Genome Projectmodulation of synaptic transmission
GO:0051447
IEA
Genome Projectnegative regulation of meiotic cell cycle
GO:0051966
IEA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0070613
IEA
Genome Projectregulation of protein processing
GO:0071158
ISS
IEA
Genome Projectpositive regulation of cell cycle arrest
GO:0071374
IEA
Genome Projectcellular response to parathyroid hormone stimulus
GO:1901621
IEA
Genome Projectnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002027
TAS
Genome Projectregulation of heart rate
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0003091
TAS
Genome Projectrenal water homeostasis
GO:0005975
TAS
Genome Projectcarbohydrate metabolic process
GO:0006006
TAS
Genome Projectglucose metabolic process
GO:0006094
TAS
Genome Projectgluconeogenesis
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006833
TAS
Genome Projectwater transport
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007202
TAS
Genome Projectactivation of phospholipase C activity
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0010881
TAS
Genome Projectregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0019433
TAS
Genome Projecttriglyceride catabolic process
GO:0034199
TAS
Genome Projectactivation of protein kinase A activity
GO:0035556
TAS
Genome Projectintracellular signal transduction
GO:0035584
TAS
Genome Projectcalcium-mediated signaling using intracellular calcium source
GO:0043393
TAS
Genome Projectregulation of protein binding
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045667
IDA
Genome Projectregulation of osteoblast differentiation
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:0051480
TAS
Genome Projectcytosolic calcium ion homeostasis
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0055117
TAS
Genome Projectregulation of cardiac muscle contraction
GO:0060314
TAS
Genome Projectregulation of ryanodine-sensitive calcium-release channel activity
GO:0061136
IDA
Genome Projectregulation of proteasomal protein catabolic process
GO:0071333
IDA
Genome Projectcellular response to glucose stimulus
GO:0071377
TAS
Genome Projectcellular response to glucagon stimulus
GO:0071872
TAS
Genome Projectcellular response to epinephrine stimulus
GO:0086064
TAS
Genome Projectcell communication by electrical coupling involved in cardiac conduction
GO:2000810
IDA
Genome Projectregulation of bicellular tight junction assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004691
IDA
ISS
NAS, IEA
Genome ProjectcAMP-dependent protein kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0004712
IDA
Genome Projectprotein serine/threonine/tyrosine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding
GO:0034237
IPI
Genome Projectprotein kinase A regulatory subunit binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005952
NAS, IEA
Genome ProjectcAMP-dependent protein kinase complex
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0031594
IEA
Genome Projectneuromuscular junction
GO:0043005
IEA
Genome Projectneuron projection
GO:0043234
IEA
Genome Projectprotein complex
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097546
TAS, IEA
Genome Projectciliary base
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS
Genome Projectcytosol
GO:0005929
IEA
Genome Projectcilium
GO:0031514
IEA
Genome Projectmotile cilium
GO:0031588
IDA
Genome Projectnucleotide-activated protein kinase complex
GO:0034704
TAS
Genome Projectcalcium channel complex
GO:0042995
IEA
Genome Projectcell projection
GO:0044853
IDA
Genome Projectplasma membrane raft
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0097225
IDA
Genome Projectsperm midpiece

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.