Gene: ENSG00000069702 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000069702
Transcript Identifier
ENST00000525962
Gene Type
Coding gene
Location
1 : 91683739-91861531 : negative

Family Information

Homologous gene family
HOM03P027924
(3 genes in 2 species)
specific family

Descriptions

gene_descr
transforming growth factor, beta receptor III

Identifiers

Type Value
pidENSP00000436127
HGNC11774
UniprotQ03167

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001837
IDA
Genome Projectepithelial to mesenchymal transition
GO:0001889
ISS
Genome Projectliver development
GO:0003007
ISS
Genome Projectheart morphogenesis
GO:0006461
IEA
Genome Projectprotein complex assembly
GO:0006955
IMP
Genome Projectimmune response
GO:0007179
IDA, IMP
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007181
IEA
Genome Projecttransforming growth factor beta receptor complex assembly
GO:0016049
ISS
IEA
Genome Projectcell growth
GO:0016477
ISS
Genome Projectcell migration
GO:0030509
IDA
Genome ProjectBMP signaling pathway
GO:0030511
IEA
Genome Projectpositive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512
IEA
Genome Projectnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0032354
IDA
Genome Projectresponse to follicle-stimulating hormone
GO:0034695
IDA
Genome Projectresponse to prostaglandin E
GO:0034699
IDA
Genome Projectresponse to luteinizing hormone
GO:0035556
IMP
Genome Projectintracellular signal transduction
GO:0043393
IEA
Genome Projectregulation of protein binding
GO:0050680
ISS
Genome Projectnegative regulation of epithelial cell proliferation
GO:0051271
IDA
Genome Projectnegative regulation of cellular component movement
GO:0055010
ISS
Genome Projectventricular cardiac muscle tissue morphogenesis
GO:0060021
ISS
Genome Projectpalate development
GO:0060038
ISS
Genome Projectcardiac muscle cell proliferation
GO:0060216
ISS
Genome Projectdefinitive hemopoiesis
GO:0060317
IDA
Genome Projectcardiac epithelial to mesenchymal transition
GO:0060318
ISS
Genome Projectdefinitive erythrocyte differentiation
GO:0060347
ISS
Genome Projectheart trabecula formation
GO:0060389
IMP
Genome Projectpathway-restricted SMAD protein phosphorylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005024
IDA
Genome Projecttransforming growth factor beta-activated receptor activity
GO:0005114
IDA
Genome Projecttype II transforming growth factor beta receptor binding
GO:0005160
ISS
IEA
Genome Projecttransforming growth factor beta receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005539
ISS
TAS
Genome Projectglycosaminoglycan binding
GO:0008201
ISS
IEA
Genome Projectheparin binding
GO:0015026
IDA
Genome Projectcoreceptor activity
GO:0017134
IEA
Genome Projectfibroblast growth factor binding
GO:0030165
ISS
Genome ProjectPDZ domain binding
GO:0046332
IMP
Genome ProjectSMAD binding
GO:0048185
IEA
Genome Projectactivin binding
GO:0050431
IDA, IPI
Genome Projecttransforming growth factor beta binding
GO:0070123
IDA
IEA
Genome Projecttransforming growth factor beta receptor activity, type III

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005578
IEA
Genome Projectproteinaceous extracellular matrix
GO:0005615
IDA
TAS, IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
ISS
IEA
Genome Projectintegral component of plasma membrane
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
ISS
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0034673
IDA
Genome Projectinhibin-betaglycan-ActRII complex
GO:0043235
IDA
IEA
Genome Projectreceptor complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001507Zona pellucida domain
IPR017977Zona pellucida domain, conserved site

No MapMan annotations defined for this gene.