Gene: ENSG00000068001 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000068001
Transcript Identifier
ENST00000442581
Gene Type
Coding gene
Location
3 : 50318129-50320489 : negative

Family Information

Homologous gene family
HOM03P007094
(12 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P062748
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
hyaluronoglucosaminidase 2

Identifiers

Type Value
pidENSP00000406657
HGNC5321
UniprotQ12891

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000302
IDA
Genome Projectresponse to reactive oxygen species
GO:0001822
ISS
Genome Projectkidney development
GO:0002244
IEA
Genome Projecthematopoietic progenitor cell differentiation
GO:0005975
TAS, IEA
Genome Projectcarbohydrate metabolic process
GO:0006027
IDA
Genome Projectglycosaminoglycan catabolic process
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009615
IDA
Genome Projectresponse to virus
GO:0010259
IEA
Genome Projectmulticellular organismal aging
GO:0010764
IDA
Genome Projectnegative regulation of fibroblast migration
GO:0019064
IDA
Genome Projectfusion of virus membrane with host plasma membrane
GO:0019087
IDA
ISS
Genome Projecttransformation of host cell by virus
GO:0030203
TAS
Genome Projectglycosaminoglycan metabolic process
GO:0030212
TAS
Genome Projecthyaluronan metabolic process
GO:0030214
IDA
TAS
Genome Projecthyaluronan catabolic process
GO:0030308
IDA
Genome Projectnegative regulation of cell growth
GO:0035810
ISS
Genome Projectpositive regulation of urine volume
GO:0042117
IDA
Genome Projectmonocyte activation
GO:0042307
ISS
IEA
Genome Projectpositive regulation of protein import into nucleus
GO:0043407
IDA
Genome Projectnegative regulation of MAP kinase activity
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0044344
IDA
Genome Projectcellular response to fibroblast growth factor stimulus
GO:0045944
ISS
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046677
IEP
Genome Projectresponse to antibiotic
GO:0046718
ISS
Genome Projectviral entry into host cell
GO:0048705
IEA
Genome Projectskeletal system morphogenesis
GO:0050729
IDA
Genome Projectpositive regulation of inflammatory response
GO:0051216
IEP
Genome Projectcartilage development
GO:0051607
IEA
Genome Projectdefense response to virus
GO:0051898
IDA
Genome Projectnegative regulation of protein kinase B signaling
GO:0060586
IEA
Genome Projectmulticellular organismal iron ion homeostasis
GO:0061099
IDA
Genome Projectnegative regulation of protein tyrosine kinase activity
GO:0070295
ISS
Genome Projectrenal water absorption
GO:0071347
IDA
Genome Projectcellular response to interleukin-1
GO:0071356
IEP
Genome Projectcellular response to tumor necrosis factor
GO:0071493
IDA
Genome Projectcellular response to UV-B
GO:0071560
IDA
Genome Projectcellular response to transforming growth factor beta stimulus
GO:2000484
IDA
Genome Projectpositive regulation of interleukin-8 secretion
GO:2000778
IDA
Genome Projectpositive regulation of interleukin-6 secretion
GO:2001238
ISS
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001105
IEA
Genome ProjectRNA polymerase II transcription coactivator activity
GO:0001618
IDA
IEA
Genome Projectvirus receptor activity
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004415
IDA
TAS
Genome Projecthyalurononglucosaminidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005540
IDA
Genome Projecthyaluronic acid binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016798
IEA
Genome Projecthydrolase activity, acting on glycosyl bonds
GO:0019899
IPI
Genome Projectenzyme binding
GO:0030294
IDA
Genome Projectreceptor signaling protein tyrosine kinase inhibitor activity
GO:0030971
IPI
Genome Projectreceptor tyrosine kinase binding
GO:0033906
IDA
Genome Projecthyaluronoglucuronidase activity
GO:0050431
ISS
IEA
Genome Projecttransforming growth factor beta binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
ISS
Genome ProjectGolgi membrane
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005764
IDA
Genome Projectlysosome
GO:0005783
NAS
Genome Projectendoplasmic reticulum
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005902
IDA
Genome Projectmicrovillus
GO:0009986
IDA
ISS
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030139
IDA
Genome Projectendocytic vesicle
GO:0031225
IEA
Genome Projectanchored component of membrane
GO:0031362
IDA
IEA
Genome Projectanchored component of external side of plasma membrane
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0045121
IDA
Genome Projectmembrane raft
GO:0046658
IDA
Genome Projectanchored component of plasma membrane
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0090575
ISS
IEA
Genome ProjectRNA polymerase II transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000742EGF-like domain
IPR013785Aldolase-type TIM barrel
IPR017853Glycoside hydrolase superfamily
IPR018155Hyaluronidase

No MapMan annotations defined for this gene.