Gene: ENSG00000067715 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000067715
Transcript Identifier
ENST00000552744
Gene Type
Coding gene
Location
12 : 79217520-79449124 : positive

Family Information

Homologous gene family
HOM03P001218
(55 genes in 9 species)
specific family
Orthologous gene family
ORTHO03P015093
(6 genes in 5 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
synaptotagmin I

Identifiers

Type Value
pidENSP00000447575
HGNC11509
UniprotP21579
UniprotA0A024RBE9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007269
TAS, IEA
Genome Projectneurotransmitter secretion
GO:0016079
IBA
IEA
Genome Projectsynaptic vesicle exocytosis
GO:0050806
ISS
IEA
Genome Projectpositive regulation of synaptic transmission
GO:0051966
ISS
IEA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0098746
ISS
IEA
Genome Projectfast, calcium ion-dependent exocytosis of neurotransmitter
GO:0005513
TAS
Genome Projectdetection of calcium ion
GO:0007268
TAS
Genome Projectsynaptic transmission
GO:0014047
TAS
Genome Projectglutamate secretion
GO:0017157
TAS
Genome Projectregulation of exocytosis
GO:0017158
IBA
Genome Projectregulation of calcium ion-dependent exocytosis
GO:0048488
IBA
Genome Projectsynaptic vesicle endocytosis
GO:0048791
IBA
Genome Projectcalcium ion-dependent exocytosis of neurotransmitter
GO:0051260
TAS
Genome Projectprotein homooligomerization
GO:1903305
ISS
Genome Projectregulation of regulated secretory pathway
GO:1903861
IDA
Genome Projectpositive regulation of dendrite extension

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005509
IBA
IEA
Genome Projectcalcium ion binding
GO:0048306
IEA
Genome Projectcalcium-dependent protein binding
GO:0000149
ISS
Genome ProjectSNARE binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005544
ISS
TAS
Genome Projectcalcium-dependent phospholipid binding
GO:0005545
TAS
Genome Project1-phosphatidylinositol binding
GO:0005546
IBA
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0017075
ISS
TAS
Genome Projectsyntaxin-1 binding
GO:0030276
IBA
Genome Projectclathrin binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050750
IDA
Genome Projectlow-density lipoprotein particle receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
Genome Projectmembrane
GO:0030141
IEA
Genome Projectsecretory granule
GO:0030672
IBA
TAS, IEA
Genome Projectsynaptic vesicle membrane
GO:0042734
IEA
Genome Projectpresynaptic membrane
GO:0043005
ISS
IEA
Genome Projectneuron projection
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IBA
TAS
Genome Projectplasma membrane
GO:0008021
TAS
Genome Projectsynaptic vesicle
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0042584
IEA
Genome Projectchromaffin granule membrane
GO:0045202
IEA
Genome Projectsynapse
GO:0060201
TAS
Genome Projectclathrin-sculpted acetylcholine transport vesicle membrane
GO:0060203
TAS
Genome Projectclathrin-sculpted glutamate transport vesicle membrane
GO:0061202
TAS
Genome Projectclathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0070083
TAS
Genome Projectclathrin-sculpted monoamine transport vesicle membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR001565Synaptotagmin
IPR015428Synaptotagmin 1

No MapMan annotations defined for this gene.