Gene: ENSG00000067182 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000067182
Transcript Identifier
ENST00000162749
Gene Type
Coding gene
Location
12 : 6329312-6341814 : negative

Family Information

Homologous gene family
HOM03P025735
(3 genes in 2 species)
specific family

Descriptions

gene_descr
tumor necrosis factor receptor superfamily, member 1A

Identifiers

Type Value
pidENSP00000162749
HGNC11916
UniprotP19438

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006693
IEA
Genome Projectprostaglandin metabolic process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006952
IEA
Genome Projectdefense response
GO:0006954
ISS
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
TAS, IEA
Genome Projectcell surface receptor signaling pathway
GO:0008625
TAS
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0008630
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0016032
IEA
Genome Projectviral process
GO:0019221
ISS
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0033209
TAS, IEA
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0042511
IMP
Genome Projectpositive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042742
IEA
Genome Projectdefense response to bacterium
GO:0043123
IEP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944
IMP
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0050729
ISS
IEA
Genome Projectpositive regulation of inflammatory response
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus
GO:0071550
TAS
Genome Projectdeath-inducing signaling complex assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005031
TAS, IEA
Genome Projecttumor necrosis factor-activated receptor activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IDA
IEA
Genome ProjectGolgi membrane
GO:0005576
TAS, NAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043235
IDA
Genome Projectreceptor complex
GO:0045121
IDA
Genome Projectmembrane raft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000488Death domain
IPR001368TNFR/NGFR cysteine-rich region
IPR011029Death-like domain
IPR020419Tumour necrosis factor receptor 1A

No MapMan annotations defined for this gene.