Gene: ENSG00000067066 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000067066
Transcript Identifier
ENST00000340126
Gene Type
Coding gene
Location
2 : 230416297-230542946 : positive

Family Information

Homologous gene family
HOM03P004298
(22 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
SP100 nuclear antigen

Identifiers

Type Value
pidENSP00000343023
HGNC11206
UniprotP23497

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000723
IMP
Genome Projecttelomere maintenance
GO:0006338
IBA
Genome Projectchromatin remodeling
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006978
IDA
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0010596
IMP
Genome Projectnegative regulation of endothelial cell migration
GO:0016032
IEA
Genome Projectviral process
GO:0016925
TAS
Genome Projectprotein sumoylation
GO:0019221
TAS
Genome Projectcytokine-mediated signaling pathway
GO:0032526
IDA
Genome Projectresponse to retinoic acid
GO:0032897
IDA
Genome Projectnegative regulation of viral transcription
GO:0034097
IDA
Genome Projectresponse to cytokine
GO:0034340
IDA, IMP
Genome Projectresponse to type I interferon
GO:0034341
IDA, IMP
Genome Projectresponse to interferon-gamma
GO:0043392
IDA
Genome Projectnegative regulation of DNA binding
GO:0043433
IDA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0045765
IMP
Genome Projectregulation of angiogenesis
GO:0045892
IDA, IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0046826
IMP
Genome Projectnegative regulation of protein export from nucleus
GO:0048384
IC
Genome Projectretinoic acid receptor signaling pathway
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051271
IMP
Genome Projectnegative regulation of cellular component movement
GO:0060333
TAS, IC
Genome Projectinterferon-gamma-mediated signaling pathway
GO:0060337
IC
Genome Projecttype I interferon signaling pathway
GO:1902041
IMP
Genome Projectregulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902044
IMP
Genome Projectregulation of Fas signaling pathway
GO:1903507
IDA
Genome Projectnegative regulation of nucleic acid-templated transcription

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IBA
Genome Projectchromatin binding
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0003714
IDA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042803
IPI
Genome Projectprotein homodimerization activity
GO:0070087
IPI
Genome Projectchromo shadow domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000784
IDA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005730
IDA, IMP
Genome Projectnucleolus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0016605
IDA
IEA
Genome ProjectPML body
GO:0034399
IDA
Genome Projectnuclear periphery
GO:0030870
IDA
Genome ProjectMre11 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000770SAND domain
IPR004865Homogeneously-staining region
IPR009071High mobility group box domain
IPR010919SAND domain-like
IPR031076High mobility group protein HMGB1

No MapMan annotations defined for this gene.