Gene: ENSG00000066230 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000066230
Transcript Identifier
ENST00000264938
Gene Type
Coding gene
Location
5 : 473379-524322 : negative

Family Information

Homologous gene family
HOM03P000250
(148 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P009052
(9 genes in 4 species)
specific family

Descriptions

gene_descr
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3

Identifiers

Type Value
pidENSP00000264938
HGNC11073
UniprotP48764

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002028
IEA
Genome Projectregulation of sodium ion transport
GO:0006810
IEA
Genome Projecttransport
GO:0006811
TAS, IEA
Genome Projection transport
GO:0006812
IEA
Genome Projectcation transport
GO:0006814
IEA
Genome Projectsodium ion transport
GO:0006885
IEA
Genome Projectregulation of pH
GO:0006898
IEA
Genome Projectreceptor-mediated endocytosis
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0035725
ISS
IEA
Genome Projectsodium ion transmembrane transport
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0055085
TAS, IEA
Genome Projecttransmembrane transport
GO:1902600
IEA
Genome Projecthydrogen ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0015297
IEA
Genome Projectantiporter activity
GO:0015299
IEA
Genome Projectsolute:proton antiporter activity
GO:0015385
ISS
IEA
Genome Projectsodium:proton antiporter activity
GO:0030165
ISS
IEA
Genome ProjectPDZ domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA
ISS
TAS, IEA
Genome Projectplasma membrane
GO:0005903
ISS
IEA
Genome Projectbrush border
GO:0009986
ISS
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
ISS
IEA
Genome Projectapical plasma membrane
GO:0031526
ISS
IEA
Genome Projectbrush border membrane
GO:0031988
IEA
Genome Projectmembrane-bounded vesicle
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004709Na+/H+ exchanger
IPR006153Cation/H+ exchanger
IPR018410Na+/H+ exchanger, isoforms 3/5
IPR018422Cation/H+ exchanger, CPA1 family

No MapMan annotations defined for this gene.