Gene: ENSG00000065534 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000065534
Transcript Identifier
ENST00000475616
Gene Type
Coding gene
Location
3 : 123614105-123793841 : negative

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P071534
(2 genes in 2 species)
specific family

Descriptions

gene_descr
myosin light chain kinase

Identifiers

Type Value
pidENSP00000418335
HGNC7590
UniprotQ15746

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002230
IMP
Genome Projectpositive regulation of defense response to virus by host
GO:0006468
TAS, IEA
Genome Projectprotein phosphorylation
GO:0006936
TAS
Genome Projectmuscle contraction
GO:0006939
ISS, IBA
Genome Projectsmooth muscle contraction
GO:0007015
IBA
Genome Projectactin filament organization
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0014820
ISS
Genome Projecttonic smooth muscle contraction
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030335
IDA
Genome Projectpositive regulation of cell migration
GO:0032060
IMP
Genome Projectbleb assembly
GO:0051928
IDA
Genome Projectpositive regulation of calcium ion transport
GO:0060414
IMP
Genome Projectaorta smooth muscle tissue morphogenesis
GO:0071476
IDA
Genome Projectcellular hypotonic response
GO:0090303
IDA
Genome Projectpositive regulation of wound healing
GO:0098779
IGI
Genome Projectmitophagy in response to mitochondrial depolarization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003779
IEA
Genome Projectactin binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004683
IBA
Genome Projectcalmodulin-dependent protein kinase activity
GO:0004687
IDA
TAS, IEA
Genome Projectmyosin light chain kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005516
IEA
Genome Projectcalmodulin binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001725
IDA
Genome Projectstress fiber
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005911
IEA
Genome Projectcell-cell junction
GO:0030027
IDA
IEA
Genome Projectlamellipodium
GO:0032154
IDA
IEA
Genome Projectcleavage furrow
GO:0042995
IEA
Genome Projectcell projection
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003598Immunoglobulin subtype 2
IPR003599Immunoglobulin subtype
IPR003961Fibronectin type III
IPR007110Immunoglobulin-like domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR013098Immunoglobulin I-set
IPR013783Immunoglobulin-like fold
IPR015725Telokin/Myosin light chain kinase
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.