Gene: ENSG00000060140 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000060140
Transcript Identifier
ENST00000075503
Gene Type
Coding gene
Location
12 : 10620144-10634618 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family

Descriptions

gene_descr
serine/threonine/tyrosine kinase 1

Identifiers

Type Value
pidENSP00000075503
HGNC18889
UniprotQ6J9G0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IBA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030154
IBA
Genome Projectcell differentiation
GO:0038083
IBA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0042127
IBA
Genome Projectregulation of cell proliferation
GO:0045087
IBA
Genome Projectinnate immune response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004715
IBA
IEA
Genome Projectnon-membrane spanning protein tyrosine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0005102
IBA
Genome Projectreceptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031234
IBA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain

No MapMan annotations defined for this gene.