Gene: ENSG00000055130 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000055130
Transcript Identifier
ENST00000325222
Gene Type
Coding gene
Location
7 : 148730123-148800582 : positive

Family Information

Homologous gene family
HOM03P000158
(196 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P010971
(8 genes in 8 species)
specific family

Descriptions

gene_descr
cullin 1

Identifiers

Type Value
pidENSP00000326804
HGNC2551
UniprotQ13616
UniprotA0A090N7U0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006511
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006513
IEA
Genome Projectprotein monoubiquitination
GO:0006915
IEA
Genome Projectapoptotic process
GO:0008283
IEA
Genome Projectcell proliferation
GO:0009887
IEA
Genome Projectorgan morphogenesis
GO:0000082
TAS
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007219
TAS
Genome ProjectNotch signaling pathway
GO:0007623
TAS
Genome Projectcircadian rhythm
GO:0008285
TAS
Genome Projectnegative regulation of cell proliferation
GO:0016032
IEA
Genome Projectviral process
GO:0016567
IDA
IEA
Genome Projectprotein ubiquitination
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031146
IDA
ISS
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042787
IBA
Genome Projectprotein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0051437
TAS
Genome Projectpositive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
GO:0051439
TAS
Genome Projectregulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0097193
TAS
Genome Projectintrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031625
IEA
Genome Projectubiquitin protein ligase binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0061630
IBA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031461
IDA
IEA
Genome Projectcullin-RING ubiquitin ligase complex
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0019005
IDA
ISS
Genome ProjectSCF ubiquitin ligase complex
GO:1990452
IPI
Genome ProjectParkin-FBXW7-Cul1 ubiquitin ligase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001373Cullin, N-terminal
IPR011991Winged helix-turn-helix DNA-binding domain
IPR016157Cullin, conserved site
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain
IPR019559Cullin protein, neddylation domain

No MapMan annotations defined for this gene.