Gene: ENSG00000050748 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000050748
Transcript Identifier
ENST00000455781
Gene Type
Coding gene
Location
5 : 180236384-180280561 : negative

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P011492
(7 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
mitogen-activated protein kinase 9

Identifiers

Type Value
pidENSP00000389338
HGNC6886
UniprotP45984

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001836
IEA
Genome Projectrelease of cytochrome c from mitochondria
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006468
IMP
IEA
Genome Projectprotein phosphorylation
GO:0006626
IEA
Genome Projectprotein targeting to mitochondrion
GO:0006919
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006950
TAS
Genome Projectresponse to stress
GO:0007254
IDA
TAS, IEA
Genome ProjectJNK cascade
GO:0007258
IEA
Genome ProjectJUN phosphorylation
GO:0007417
IEA
Genome Projectcentral nervous system development
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0010744
IMP
Genome Projectpositive regulation of macrophage derived foam cell differentiation
GO:0010770
IEA
Genome Projectpositive regulation of cell morphogenesis involved in differentiation
GO:0014075
IEA
Genome Projectresponse to amine
GO:0016310
IEA
Genome Projectphosphorylation
GO:0031175
IEA
Genome Projectneuron projection development
GO:0031394
IEA
Genome Projectpositive regulation of prostaglandin biosynthetic process
GO:0031396
IEA
Genome Projectregulation of protein ubiquitination
GO:0032308
IEA
Genome Projectpositive regulation of prostaglandin secretion
GO:0032722
IEA
Genome Projectpositive regulation of chemokine production
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0034644
IEA
Genome Projectcellular response to UV
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042752
ISS
IEA
Genome Projectregulation of circadian rhythm
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043280
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045429
IEA
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0046328
IEA
Genome Projectregulation of JNK cascade
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0048511
IEA
Genome Projectrhythmic process
GO:0051090
TAS
Genome Projectregulation of sequence-specific DNA binding transcription factor activity
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade
GO:0051770
IEA
Genome Projectpositive regulation of nitric-oxide synthase biosynthetic process
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071347
IEA
Genome Projectcellular response to interleukin-1
GO:0071356
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus
GO:2001235
IEA
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004705
IDA
IEA
Genome ProjectJUN kinase activity
GO:0004707
IEA
Genome ProjectMAP kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008134
IDA
IEA
Genome Projecttranscription factor binding
GO:0008656
IEA
Genome Projectcysteine-type endopeptidase activator activity involved in apoptotic process
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031435
IEA
Genome Projectmitogen-activated protein kinase kinase kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
TAS, IEA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003527Mitogen-activated protein (MAP) kinase, conserved site
IPR008271Serine/threonine-protein kinase, active site
IPR008351Mitogen-activated protein (MAP) kinase, JNK
IPR011009Protein kinase-like domain

No MapMan annotations defined for this gene.