Gene: ENSG00000047648 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000047648
Transcript Identifier
ENST00000337414
Gene Type
Coding gene
Location
X : 11138863-11664828 : negative

Family Information

Homologous gene family
HOM03P000257
(144 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P074913
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Rho GTPase activating protein 6

Identifiers

Type Value
pidENSP00000338967
HGNC676
UniprotO43182

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007202
IDA
Genome Projectactivation of phospholipase C activity
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007266
TAS, NAS
Genome ProjectRho protein signal transduction
GO:0009967
TAS
Genome Projectpositive regulation of signal transduction
GO:0010518
IDA
Genome Projectpositive regulation of phospholipase activity
GO:0030041
NAS
Genome Projectactin filament polymerization
GO:0043087
IEA
Genome Projectregulation of GTPase activity
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0048041
IEA
Genome Projectfocal adhesion assembly
GO:0051056
TAS
Genome Projectregulation of small GTPase mediated signal transduction
GO:0051497
IMP
Genome Projectnegative regulation of stress fiber assembly
GO:0051895
IMP
Genome Projectnegative regulation of focal adhesion assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005070
TAS
Genome ProjectSH3/SH2 adaptor activity
GO:0005096
IEA
Genome ProjectGTPase activator activity
GO:0016004
IDA
Genome Projectphospholipase activator activity
GO:0017124
IEA
Genome ProjectSH3 domain binding
GO:0043274
IPI
Genome Projectphospholipase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IMP
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005884
NAS
Genome Projectactin filament
GO:0015629
ISS
IEA
Genome Projectactin cytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000198Rho GTPase-activating protein domain
IPR008936Rho GTPase activation protein
IPR030772Rho GTPase-activating protein 6

No MapMan annotations defined for this gene.