Gene: ENSG00000043591 (Homo sapiens)

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Gene Identifier
ENSG00000043591
Transcript Identifier
ENST00000369295
Gene Type
Coding gene
Location
10 : 114044133-114045566 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P064433
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
adrenoceptor beta 1

Identifiers

Type Value
pidENSP00000358301
HGNC285
UniprotP08588

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001659
IBA
Genome Projecttemperature homeostasis
GO:0001996
IBA
IEA
Genome Projectpositive regulation of heart rate by epinephrine-norepinephrine
GO:0001997
IEA
Genome Projectpositive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0002024
IEA
Genome Projectdiet induced thermogenesis
GO:0002025
IBA
IEA
Genome Projectvasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007189
IEA
Genome Projectadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190
TAS
Genome Projectactivation of adenylate cyclase activity
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0009409
IEA
Genome Projectresponse to cold
GO:0030819
IDA
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0031649
IEA
Genome Projectheat generation
GO:0035556
IDA
Genome Projectintracellular signal transduction
GO:0040015
IEA
Genome Projectnegative regulation of multicellular organism growth
GO:0042596
IEA
Genome Projectfear response
GO:0043547
IDA
Genome Projectpositive regulation of GTPase activity
GO:0043950
IDA
Genome Projectpositive regulation of cAMP-mediated signaling
GO:0045823
IEA
Genome Projectpositive regulation of heart contraction
GO:0050873
IEA
Genome Projectbrown fat cell differentiation
GO:0071880
IDA
Genome Projectadenylate cyclase-activating adrenergic receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004935
IEA
Genome Projectadrenergic receptor activity
GO:0004939
TAS
Genome Projectbeta-adrenergic receptor activity
GO:0004940
TAS, IEA
Genome Projectbeta1-adrenergic receptor activity
GO:0005057
IDA
Genome Projectreceptor signaling protein activity
GO:0005088
IDA
Genome ProjectRas guanyl-nucleotide exchange factor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0030165
IPI
Genome ProjectPDZ domain binding
GO:0031694
IPI
Genome Projectalpha-2A adrenergic receptor binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity
GO:0051379
IBA
Genome Projectepinephrine binding
GO:0051380
IBA
Genome Projectnorepinephrine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005768
IEA
Genome Projectendosome
GO:0005769
IDA
IEA
Genome Projectearly endosome
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000507Beta 1 adrenoceptor
IPR002233Adrenoceptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.