Gene: ENSG00000035720 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000035720
Transcript Identifier
ENST00000396225
Gene Type
Coding gene
Location
4 : 67558810-67606357 : positive

Family Information

Homologous gene family
HOM03P021290
(4 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P065304
(2 genes in 2 species)
specific family

Descriptions

gene_descr
signal transducing adaptor family member 1

Identifiers

Type Value
pidENSP00000379527
HGNC24133
UniprotQ9ULZ2
UniprotA0A024RD91

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007169
ISS
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0010628
ISS
Genome Projectpositive regulation of gene expression
GO:0010760
ISS
Genome Projectnegative regulation of macrophage chemotaxis
GO:0042326
ISS
Genome Projectnegative regulation of phosphorylation
GO:0050861
IDA
Genome Projectpositive regulation of B cell receptor signaling pathway
GO:0060100
ISS
Genome Projectpositive regulation of phagocytosis, engulfment
GO:0071222
ISS
Genome Projectcellular response to lipopolysaccharide
GO:1900028
ISS
Genome Projectnegative regulation of ruffle assembly
GO:1902227
ISS
Genome Projectnegative regulation of macrophage colony-stimulating factor signaling pathway
GO:1903980
ISS
Genome Projectpositive regulation of microglial cell activation
GO:1903997
IDA
Genome Projectpositive regulation of non-membrane spanning protein tyrosine kinase activity
GO:1904151
ISS
Genome Projectpositive regulation of microglial cell mediated cytotoxicity
GO:2000251
ISS
Genome Projectpositive regulation of actin cytoskeleton reorganization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001784
IPI
Genome Projectphosphotyrosine binding
GO:0005068
ISS
Genome Projecttransmembrane receptor protein tyrosine kinase adaptor activity
GO:0005070
IPI
Genome ProjectSH3/SH2 adaptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005543
NAS
Genome Projectphospholipid binding
GO:0019901
IPI
Genome Projectprotein kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0043234
IDA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000980SH2 domain
IPR001849Pleckstrin homology domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.