Gene: ENSG00000035403 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000035403
Transcript Identifier
ENST00000211998
Gene Type
Coding gene
Location
10 : 73998208-74118169 : positive

Family Information

Homologous gene family
HOM03P021425
(4 genes in 4 species)
specific family

Descriptions

gene_descr
vinculin

Identifiers

Type Value
pidENSP00000211998
HGNC12665
UniprotP18206
UniprotV9HWK2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002009
IMP
Genome Projectmorphogenesis of an epithelium
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0006928
TAS
Genome Projectmovement of cell or subcellular component
GO:0006936
TAS
Genome Projectmuscle contraction
GO:0007155
TAS, IEA
Genome Projectcell adhesion
GO:0007160
TAS, IEA
Genome Projectcell-matrix adhesion
GO:0007596
TAS
Genome Projectblood coagulation
GO:0030032
ISS
IEA
Genome Projectlamellipodium assembly
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030334
IEA
Genome Projectregulation of cell migration
GO:0030336
TAS
Genome Projectnegative regulation of cell migration
GO:0034333
IMP
Genome Projectadherens junction assembly
GO:0034394
IMP
Genome Projectprotein localization to cell surface
GO:0043297
IMP
Genome Projectapical junction assembly
GO:0048675
IEA
Genome Projectaxon extension
GO:0070527
IMP
Genome Projectplatelet aggregation
GO:0090136
IMP
Genome Projectepithelial cell-cell adhesion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002162
IPI
Genome Projectdystroglycan binding
GO:0003779
IDA
Genome Projectactin binding
GO:0005198
IEA
Genome Projectstructural molecule activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
ISS
Genome Projectbeta-catenin binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0045294
IPI
Genome Projectalpha-catenin binding
GO:0045296
ISS
Genome Projectcadherin binding
GO:0051015
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005623
ISS
Genome Projectcell
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
TAS, IEA
Genome Projectcytoskeleton
GO:0005886
ISS
IEA
Genome Projectplasma membrane
GO:0005903
ISS
Genome Projectbrush border
GO:0005911
ISS
IEA
Genome Projectcell-cell junction
GO:0005912
ISS
IEA
Genome Projectadherens junction
GO:0005913
IDA
Genome Projectcell-cell adherens junction
GO:0005915
ISS
Genome Projectzonula adherens
GO:0005916
IEA
Genome Projectfascia adherens
GO:0005925
IDA
ISS
IEA
Genome Projectfocal adhesion
GO:0015629
IEA
Genome Projectactin cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030055
NAS
Genome Projectcell-substrate junction
GO:0043034
IDA
ISS
Genome Projectcostamere
GO:0043234
IDA
Genome Projectprotein complex
GO:0045121
IDA
Genome Projectmembrane raft
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0090636
ISS
Genome Projectouter dense plaque of desmosome
GO:0090637
ISS
Genome Projectinner dense plaque of desmosome
GO:1903561
IDA
Genome Projectextracellular vesicle
GO:1990357
ISS
Genome Projectterminal web

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000633Vinculin, conserved site
IPR006077Vinculin/alpha-catenin

No MapMan annotations defined for this gene.