Gene: ENSG00000033327 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000033327
Transcript Identifier
ENST00000361507
Gene Type
Coding gene
Location
11 : 78219272-78417720 : negative

Family Information

Homologous gene family
HOM03P011702
(7 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P069672
(2 genes in 2 species)
specific family

Descriptions

gene_descr
GRB2-associated binding protein 2

Identifiers

Type Value
pidENSP00000354952
HGNC14458
UniprotQ9UQC2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007169
IDA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0030316
IMP
Genome Projectosteoclast differentiation
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0043306
ISS
Genome Projectpositive regulation of mast cell degranulation
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048015
ISS
Genome Projectphosphatidylinositol-mediated signaling

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005068
IDA
Genome Projecttransmembrane receptor protein tyrosine kinase adaptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005547
ISS
Genome Projectphosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325
ISS
Genome Projectphosphatidylinositol-3,4-bisphosphate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001849Pleckstrin homology domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.